In this episode, Josh Reynolds, PhD, Founder and CEO of Atlas Biotech, joins host Maxwell Murray to discuss how functional genomics can change the odds in oncology drug development. 95% of oncology drugs fail in clinical trials. Josh and his team are building tools to address that — starting with qDMS, a platform that maps how every possible mutation in a drug target affects drug response, giving pharma companies a data set that currently does not exist.

They cover Josh's path from PhD researcher to founder, what it takes to build a lab from scratch outside academia, and what changed when the story finally caught up with the science.

In this episode, Marwan Elwaraki, Co-founder and iOS developer of Sweet Dreams, joins host Maxwell Murray to share how a family-centric companion app can reduce alert overload without replacing first-party safety alerts.

They discuss building an “invisible app” experience using Apple surfaces (Lock Screen, Live Activities/Dynamic Island, Apple Watch, CarPlay) so glucose is ambiently visible at a glance, plus touches like snooze from the lock screen, profile-based alerting (sleep/work/school), and lightweight caregiver pings/acknowledgements.

The conversation ties to Radian’s CGM UX study (A Silent Burden), covering real-world signals of reduced burden (fewer app opens, lower alert thresholds), gaps like customizable haptics and watch-first data flows, and why open, developer-friendly data access would unlock safer, quieter care.

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Links 🔗

https://www.weareradian.com/

https://www.linkedin.com/company/weareradian/

https://www.weareradian.com/cgm-study-alerts

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Huge thanks to Caleb Johnson at Speech Craft Audio for the production of this episode.

https://www.speechcraftaudio.com/

https://www.linkedin.com/company/speech-craft-audio/

Across this wide-ranging conversation, John and Radian’s Maxwell Murray explore:

→How Mass General Brigham scaled a high-acuity home-hospital program

→How digital health acted as a critical “air-traffic control” system for at home care

→ Partnering with industry (e.g., Best Buy Health) without losing clinical focus

→ Org readiness: adoption, integration, and the Epic interfaces that actually matter

→ Culture change: why behavior shifts lag technology—and how leaders manage it

→ AI and automation: where it’s adding value now, where it’s not, and what comes next

Whether you’re building digital health products, scaling healthcare operations, or exploring the frontier of AI in medicine, John’s insights provide a roadmap for what’s next.

👉 Subscribe to the Radian Podcast for more conversations with the leaders shaping digital health.

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