eBioMedicine in conversation with

Eoin Kelleher on sleep and chronic pain across the lifespan

Tue, 17 Feb 2026 23:00:00 +0000

Dr Eoin Kelleher, anaesthesiologist and expert in sleep and chronic pain, joins eBioMedicine Senior Editor Dr Rida Ansari to discuss the relationship between sleep and chronic pain across the lifespan. The conversation examines biological mechanisms, clinical implications, and everyday relevance, drawing on insights from the paper Why sleep matters in chronic pain: evidence across the lifespan.

Click on the link to read the full articles in the eBioMedicine Series on Sleep:

Why sleep matters in chronic pain: evidence across the lifespan
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(26)00039-3/fulltext

Sleep apnea, heart health and testosterone: unravelling the triad of well-being
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(26)00038-1/fulltext

Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the launch of, The Lancet Medical Imaging and Theranostics.

You can visit https://www.thelancet.com/medical-imaging-theranostics to learn more.

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Wenqing Li on transcriptome risk scores to decipher susceptibility genes for risk stratification of gastric cancer

Mon, 07 Jul 2025 09:00:00 +0000

Dr. Wenqing Li joins Peng Zhang to discuss a recent study integrating genetics and transcriptomics for risk stratification of gastric cancer.

The conversation explores the global epidemiology of gastric cancer, its high prevalence and mortality rates, particularly in East Asia and China, and the complex interplay of genetic and environmental risk factors, notably Helicobacter pylori infection.

Read the full article:

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(25)00211-7/fulltext?dgcid=buzzsprout_icw_podcast_July_25_ebiom

Alisa Clyne and Callie Weber on the impacts of APOE-ε4 and exercise training on brain microvascular endothelial cell barrier function and metabolism

Wed, 26 Feb 2025 23:00:00 +0000

Prof Alisa Clyne and Dr Callie Weber from the University of Maryland speak to Dr Gita Thapaliya about an eBioMedicine article examining the impacts of APOE-ε4 and exercise training on brain function and metabolism.

Read the full article:

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00523-1/fulltext?dgcid=buzzsprout_icw_podcast_generic_ebiom

Boyi Yang on green space and human health

Wed, 06 Nov 2024 14:00:00 +0000

Dr. Boyi Yang joins Peng Zhang to discuss the credibility of the relationship between green space and human health.

Read the full article:
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00297-4/fulltext?dgcid=buzzsprout_icw_podcast_generic_ebiom

Lei Chen on scarless burn wound healing

Mon, 30 Sep 2024 09:00:00 +0000

Dr. Lei Chen from The First Affiliated Hospital of Sun Yat-sen University discusses her publication "Approaches to scarless burn wound healing: application of 3D printed skin substitutes with dual properties of anti-infection and balancing wound hydration levels".

Read the full article:
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00297-4/fulltext?dgcid=buzzsprout_icw_podcast_generic_ebiom

Torben Hansen on the interplay between birth weight and obesity in determining childhood and adolescent cardiometabolic risk

Wed, 28 Aug 2024 22:00:00 +0000

Prof Torben Hansen from the Novo Nordisk Foundation Centre for Basic Metabolic Research, the University of Copenhagen, speaks to Gita Thapaliya about an eBioMedicine article examining the interplay between birth weight and obesity in determining childhood and adolescent cardiometabolic risks.

Read the full article:
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00240-8/fulltext?dgcid=buzzsprout_icw_podcast_generic_ebiom

Mo Li on PARP inhibitors

Thu, 04 Jul 2024 09:00:00 +0000

Dr. Mo Li from Peking University Third Hospital discusses his publication "PARP inhibitors suppress tumours via centrosome error-induced senescence independent of DNA damage response".

Read the full article:
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00164-6/fulltext?dgcid=buzzsprout_icw_podcast_generic_ebiom

Sanja Jelic & Daniel Gottlieb on the impact of CPAP on biomarkers

Thu, 30 May 2024 13:00:00 +0000

Sanja Jelic & Daniel Gottlieb join eBioMedicine to discuss the use of continuous positive airway pressure in obstructive sleep apnoea and its impact on cardiovascular and inflammatory markers.

Read the full article:
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00050-1/fulltext?dgcid=buzzsprout_icw_podcast_generic_ebiom

Eddy Pasquier & Marion LeGrand on druggable cancer vulnerabilities

Tue, 07 Nov 2023 14:00:00 +0000

Drs. Pasquier and LeGrand join eBioMedicine to discuss their stepwise approach to unveil druggable cancer vulnerabilities and to fast-track the identification of synergistic combinations against glioblastoma.

Read the full article:
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00317-1/fulltext?dgcid=buzzsprout_icw_podcast_generic_ebiom

Alan Dangour on climate change and health

Mon, 25 Sep 2023 15:00:00 +0000

Alan Dangour joins eBioMedicine to discuss climate change and health, our recently published Series, and projects they are working on at The Wellcome Trust.

Read the full Series:
https://www.thelancet.com/series/climate-change-and-health?dgcid=buzzsprout_icw_podcast_generic_ebiom

John Cryan on the microbiome-gut-brain axis and binge drinking

Tue, 25 Jul 2023 10:00:00 +0000

John Cryan joins eBioMedicine to discuss how the microbiome-gut-brain axis regulates social cognition and craving in young binge drinkers.

Read the full article:
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00007-5/fulltext?dgcid=buzzsprout_icw_podcast_generic_ebiom

Alvaro Berbís & David McClintock on computational pathology in 2030

Thu, 04 May 2023 09:00:00 +0000

Drs Berbís and McClintock join eBioMedicine to discuss the survey they conducted with experts, forecasting the role of AI in pathology within the next decade.

Read the full article:
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(22)00609-0/fulltext?dgcid=buzzsprout_icw_podcast_ebiom_lancet

Peter Robinson and Justin Reese on Long COVID subtypes

Fri, 24 Feb 2023 16:00:00 +0000

Drs Robinson and Reese join eBioMedicine to discuss their findings on semantic phenotypic clustering long COVID subtypes observed in N3C and RECOVER programmes.

Read the full article:
Generalisable long COVID subtypes: findings from the NIH N3C and RECOVER programmes

Ke-Wu Zeng on molecular glues for cancer therapy

Wed, 18 Jan 2023 13:00:00 +0000

Drs Zeng join eBioMedicine to discuss their study of a novel molecular glue, called bufalin.

Read the full article:
Atypical E3 ligase ZFP91 promotes small-molecule-induced E2F2 transcription factor degradation for cancer therapy

Elke Fischer & Thomas Horvatits on microplastics in human tissues

Mon, 12 Sep 2022 15:00:00 +0000

Drs Fischer & Horvatits join eBioMedicine to discuss their findings of microplastics in cirrhotic liver tissues.

Read the full article:
Microplastics detected in cirrhotic liver tissue

Carmel Harrington on butyrylcholinesterase as a potential biomarker for SIDS

Tue, 19 Jul 2022 08:00:00 +0000

Dr Carmel Harrington joins eBioMedicine to discuss about their findings of a potential biomarker for sudden infant death syndrome.

Read the full article:
Butyrylcholinesterase is a potential biomarker for Sudden Infant Death Syndrome

Matthieu Pernot, Clément Papadacci & Alexandre Dizeux on brain imaging and scientific comms

Wed, 15 Jun 2022 13:00:00 +0000

Drs Matthieu Pernot, Clément Papadacci & Alexandre Dizeux join eBioMedicine to discuss about ultrasound localization microscopy, brain imaging and scientific communication.

Read the full article:
In vivo whole brain microvascular imaging in mice using transcranial 3D Ultrasound Localization Microscopy

Lilian Hunt on diversity in medical research

Fri, 22 Apr 2022 14:00:00 +0000

Dr Lilian Hunt joins eBioMedicine to discuss a series of articles we commissioned on the topic of diversity in medical research.

Read the articles :
Individual differences and diversity in human physiological responses to light
Towards equitable and trustworthy genomics research
Ensuring that biomedical AI benefits diverse populations

Jun Seok Son and Min Du on maternal exercise and offspring health

Fri, 18 Mar 2022 12:00:00 +0000

Dr Jun Seok Son and Dr Min Du join eBioMedicine to discuss maternal exercise and offspring’s health, especially diet-induced obesity and metabolic disorders.

Read the full article:
Maternal exercise intergenerationally drives muscle-based thermogenesis via activation of apelin-AMPK signaling

Marc Mansour and Victor Llombart on MYC in cancer

Fri, 18 Feb 2022 14:00:00 +0000

Professor Marc Mansour and Dr Victor Llombart join eBioMedicine to discuss the “undruggable” MYC in cancer.

Rachel Deer on long COVID

Tue, 18 Jan 2022 17:00:00 +0000

Rachel Deer joins eBioMedicine to present a study encouraging characterization of long COVID symptoms via human phenotype ontology.

Read the full article:
Characterizing Long COVID: Deep Phenotype of a Complex Condition

James Zou & David Ouyang on deep learning and hidden clinical correlates

Wed, 22 Dec 2021 11:00:00 +0000

James Zou & David Ouyang join eBioMedicine to discuss issues around deep learning and hidden clinical correlates.

Beate Kampmann, Karen Keddy, and Peter Ghazal on applying big data to childhood infectious diseases in LMICs

Tue, 14 Dec 2021 09:00:00 +0000

Prof Beate Kampmann, Dr Karen Keddy, and Prof Peter Ghazal discuss a new cross-journal Series in The Lancet Infectious Diseases and eBioMedicine addressing the potential for and challenge of applying big data to childhood infectious diseases in LMICs.

Read the full Series:
https://www.thelancet.com/series/big-data-childhood-infections-LMICs

Anthony Chirwa and Ben Morton on the importance of localised research

Tue, 16 Nov 2021 14:00:00 +0000

Dr Anthony Chirwa and Dr Ben Morton join eBioMedicine to discuss controlled infections in Streptococcus Pneumoniae and the importance of localised research.

Read the full article:
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(21)00372-8/fulltext

Jodi Sherman on the intersection between healthcare and climate change

Wed, 27 Oct 2021 11:00:00 +0000

Jodi Sherman joins Julie Stacey and Liam Messin of eBioMedicine to discuss the intersection between healthcare and climate change.

Grace Fox and Dr Manoj Lalu on the importance of patient engagement in preclinical research

Wed, 22 Sep 2021 14:00:00 +0000

How can we ensure that research being conducted is relevant to its ultimate end-users? Grace Fox and Dr Manoj Lalu join eBioMedicine to discuss the importance of patient engagement in preclinical research.

Further reading:
Patient engagement in preclinical laboratory research: A scoping review

Aleix Prat on chemotherapy and menopause

Wed, 04 Aug 2021 15:00:00 +0000

Dr Aleix Prat on the relationship between chemotherapy effectiveness and menopause in patients with breast cancer.

Further reading:
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(21)00244-9/fulltext

Viviana Simon and Maria Rescigno on mRNA vaccine dosing after prior infection

Tue, 29 Jun 2021 14:00:00 +0000

Dr. Viviana Simon and Dr. Maria Rescigno discuss their proposal that people who have recovered from symptomatic COVID-19 may require only one dose of an mRNA vaccine.

Further reading:
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(21)00194-8/fulltext