APS Publications Podcast

Interorgan Insights: Sprouting and splitting - rethinking angiogenesis in biomaterials

Wed, 20 May 2026 15:29:27 -0300

In this podcast, author Kuihua Zhan discusses the recently published article, ‘Vascularization Is Driven by Sprouting and Subsequent Splitting: Mechanisms of Physiological Angiogenesis in a Porous Biomaterial Scaffold and Intervention Insights’. The article describes engineering interventions to support the physiological vascularization of large-scale tissue scaffolds.

Vascularization Is Driven by Sprouting and Subsequent Splitting: Mechanisms of Physiological Angiogenesis in a Porous Biomaterial Scaffold and Intervention Insights

Kuihua Zhan, Lun Bai

Comprehensive Physiology 2026 16:3, e70170

https://doi.org/10.1002/cph4.70170

Time-Restricted Feeding Improves Metabolic Rhythms and Liver Bioenergetics

Tue, 19 May 2026 12:27:19 -0300

In this AI generated episode of The APS Publications Podcast featuring Function, we will dive into exciting new research that is shaping our understanding of how the body works at its most fundamental level. We spotlight the article “Short-term time-restricted feeding improves metabolic rhythms and liver mitochondrial bioenergetic function in high-fat diet-fed mice,” by Valcin et al. published recently in Function. Across the U.S. and the world, more people are developing fatty liver disease—now often called metabolic dysfunction–associated steatotic liver disease. About one in three adults are affected. What causes it? Often, long-term high-fat diets and disrupted metabolism. Inside the liver, tiny structures called mitochondria—the cell’s power plants—stop working efficiently. When that happens, the liver struggles to burn fat, energy levels drop, inflammation rises, and damage spreads to other organs. But here’s the surprising part: It’s not just what we eat that hurts these mitochondria. It’s when we eat. Ready to learn more? Listen now.

Jennifer A. Valcin, Telisha Millender-Swain, Jodi R. Paul, Brandon K. Collins, Fatme Ghandour, Sameer Al Diffalha, Jennifer S. Pollock, David M. Pollock, Scott W. Ballinger, Karen L. Gamble, Shannon M. Bailey Short-term time-restricted feeding improves metabolic rhythms and liver mitochondrial bioenergetic function in high-fat diet-fed mice Function, published February 25, 2026. DOI: 10.1152/function.082.2025

Interorgan Insights: Role of the gut microbiome in predicting PAH severity

Fri, 15 May 2026 08:52:09 -0300

In this podcast, author Arun Jose discusses the recently published article, ‘Lactobacillus Is Associated With Disease in Pulmonary Arterial Hypertension: A Prospective Cohort Study.' The prospective cohort study linked the gut microbiome, gut-derived metabolites, and disease severity in patents with pulmonary arterial hypertension undergoing right heart catheterization. Authors found that the presence of Lactobacillus was associated with less severe disease.

Lactobacillus Is Associated With Disease in Pulmonary Arterial Hypertension: A Prospective Cohort Study

Arun Jose, Senu Apewokin, Nicholas J. Ollberding, Qing Duan, Jennifer Trannguyen, Sasha Z. Prisco, Thenappan Thenappan, Anna R. Hemnes, Jean M. Elwing

Comprehensive Physiology 2026 16:3, e70161

https://doi.org/10.1002/cph4.70161

Interorgan Insights: MASLD through the lens of the mitochondrial-autophagy axis

Thu, 07 May 2026 12:05:50 -0300

In this podcast, coauthors Gaurab Bhaduri and Anchin Kalia discuss their recently published review, ‘The Mitochondrial–Autophagy Axis in MASLD: Mechanisms, Crosstalk, and Therapeutic Targets’. The review integrates contemporary evidence regarding mitochondrial dysfunction and autophagic regulation in metabolic dysfunction–associated steatotic liver disease (MASLD).

The Mitochondrial–Autophagy Axis in MASLD: Mechanisms, Crosstalk, and Therapeutic Targets
Gaurab Bhaduri, Anchin Kalia, Banshi Saboo, Sanjay Bandyopadhyay
Comprehensive Physiology 2026 16:3, e70155

https://doi.org/10.1002/cph4.70155

Interorgan Insights: Highlighting the crucial role of the vascular lymphatic system

Fri, 17 Apr 2026 12:16:38 -0300

In this podcast, author Daniela Negrini discusses the recently published review, ‘The Thoracic Lymphatic Vasculature: Inter-Organ Strategies to Achieve an Optimal Tissue Function’. The article highlights the important but often overlooked role of vascular lymphatic system and the contribution of lymphatic vasculature to the control of extracellular fluid volume and composition as it applies to the majority of the body tissues.

The Thoracic Lymphatic Vasculature: Inter-Organ Strategies to Achieve an Optimal Tissue Function

Daniela Negrini, Eleonora Solari, Cristiana Marcozzi, Andrea Moriondo

Comprehensive Physiology 2026 16:2, e70143

https://doi.org/https://doi.org/10.1002/cph4.70143

Exploring molecular shifts induced by pseudohypoxia in gray seal blubber

Fri, 10 Apr 2026 14:27:07 -0300

In this episode of The APS Publications Podcast, featuring AJP-Regulatory, Integrative and Comparative Medicine, author Laura Oller discusses her recent article, "Molecular shifts induced by pseudohypoxia in gray seal blubber: an ex vivo approach." This study explored how blubber regulates responses to chemically induced pseudohypoxia. This study showed a faster, but sustained, increase in molecular markers of hypoxia. It documents downstream molecular responses to those hypoxia-induced changes, revealing important adaptations in mechanisms that induce and sustain the hypoxia response in blubber.

Molecular shifts induced by pseudohypoxia in gray seal blubber: an ex vivo approach Laura Oller, Joel Rocha, Holly Clare Armstrong, Simon E. W. Moss, Ailsa J. Hall, and Kimberley Ann Bennett

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2026 330:4, R317-R335

Interorgan Insights: Unraveling the paradox of clinically silent cardiac stress

Thu, 02 Apr 2026 13:03:39 -0300

In this podcast, Nguyen Duc Huy Hoang discusses his recently published article, ‘Mechanosensory Silence During Cardiac Stress’. He asks the question, "Why does mechanosensory stress in the heart so often remain perceptually silent?" and hopes his group's new conceptual gating framework, Cardiac Mechanoafferent Silencing Model, will shed some light on the topic and support the prioritization of future experimental and translational investigations.

Mechanosensory Silence During Cardiac Stress

Nguyen Duc Huy Hoang

Comprehensive Physiology 2026 16:2, e70122

https://doi.org/10.1002/cph4.70122

Interorgan Insights: Microcirculation as the fundamental basis of health and disease

Tue, 24 Mar 2026 10:43:53 -0300

In this podcast, coauthors Yuan Li and Mingming Liu discuss their recently published article, ‘Functional segregation of pancreatic microcirculation reveals sex-dependent microhemodynamic signatures’. The article used a multi-scale approach to investigate pancreatic microhemodynamics in healthy male and female mice. Authors identified sexual dimorphism in pancreatic microhemodynamics that was restricted to the exocrine compartment, where blood vessels expressed different levels of CD31 and estrogen receptor ERβ. These sex-specific vascular patterns were linked to distinct systemic steroid hormone profiles, leading to fundamentally different mechanisms of blood‑flow regulation in males and females. Overall, the work identified pancreatic microvasculature as a key site where hormonal differences shape sex‑specific organ physiology.

Yuan Li, Yingyu Wang, Bing Wang, Qin Ouyang, Weiqi Liu, Xiang Xu, Xu Zhang, Mingming Liu, Ruijuan Xiu

Comprehensive Physiology 2026 16:2, e70130

https://doi.org/10.1002/cph4.70130

Interorgan Insights: Vagus nerve stimulation across disease states

Thu, 12 Mar 2026 16:03:23 -0300

In this podcast, coauthors Yifeng Bu and Imanuel Lerman discuss their recently published review, ‘A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action’. The review overviews VNS mechanisms and their translational relevance, and thus serves as a foundational resource for advancing the science and clinical deployment of precision neuromodulation and bioelectronic medicine.

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

Yifeng Bu, Alex Liang, Benjamin U. Hoffman, Dawn M. Schiehser, Oliver Case, Alan Simmons, Ruth Klaming, Andres Gottfried-Blackmore, Ravinder K. Mittal, Christopher Puleo, Hubert Lim, Imanuel Lerman

Comprehensive Physiology 2025 16:2, e70109

https://doi.org/10.1002/cph4.70109

Interorgan Insights: Improving perimenopausal health through holistic, precision-based approaches

Tue, 03 Mar 2026 14:19:39 -0400

In this podcast, coauthors Yujie Xu, Han Wu, Ru Mu, Lu Yang, Yixuan Li, and Xian Ma discuss their recently published review, 'Kisspeptin Neurons as Integrative Hub: Cross-Talk of HPO–HPT–HPA Axes in Perimenopausal Reproductive Health’. The findings highlight the multi-axis pathophysiology of perimenopausal endocrine disorders and suggest therapeutic potential for treatments targeting kisspeptin neurons as part of individualized, multi-axis approaches.

Kisspeptin Neurons as Integrative Hub: Cross-Talk of HPO–HPT–HPA Axes in Perimenopausal Reproductive Health

Yujie Xu, Han Wu, Ru Mu, Lu Yang, Yixuan Li, Xian Ma

Comprehensive Physiology 2026 16:1, e70115

https://doi.org/10.1002/cph4.70115

Interorgan Insights: Modulation of AQP1 and TGFB1 to Disrupt BMP/TGF-β Signaling in Human Pulmonary Microvascular Endothelial Cells

Fri, 13 Feb 2026 14:33:48 -0400

In this podcast, coauthors Chrysi Keskinidou and Nikolaos S. Lotsio discuss their recently published research article, ‘Disrupting BMP/TGF-β Signaling: Modulation of AQP1 and TGFB1 in Human Pulmonary Microvascular Endothelial Cells’. The article describes the authors' deep dive into the interactions between AQP1 and TGFB1 in human pulmonary vascular endothelial cells, and and provide a novel perspective on the interactions of the BMP/TGF-β signaling pathway.

Disrupting BMP/TGF-β Signaling: Modulation of AQP1 and TGFB1 in Human Pulmonary Microvascular Endothelial Cells

Chrysi Keskinidou, Nikolaos S. Lotsios, Kostas A. Papavassiliou, Athanasios G. Papavassiliou, Ioanna Dimopoulou, Anastasia Kotanidou, David Langleben, Stylianos E. Orfanos, Alice G. Vassiliou

Comprehensive Physiology 2025 15:6, e70066

https://doi.org/10.1002/cph4.70066

Interorgan Insights: Insulin and the Secret to Healthier Aging

Fri, 06 Feb 2026 15:47:10 -0400

In this podcast, corresponding author Yuan-Yuan Zhang discusses the recently published review, ‘Insulin as an Accelerator and Brake of Aging: From Molecular Landscape to Clinical Interventions’. Here, Dr. Zhang describes key findings, key takeaways, and key gaps that relate to our understanding of the role of insulin in aging and how it can be leveraged for anti-aging therapies. Listen here to learn why her and her co-authors argue that the secret to healthier aging lies with insulin and in helping it find the perfect rhythm.

Shi-Cheng Chen, Xiao-Dong Sun, Yuan-Yuan Zhang

Comprehensive Physiology 2025;15(6):e70079

https://doi.org/10.1002/cph4.70079

Navigating the frontier of AI-assisted student assignments: challenges, skills, and solutions

Thu, 29 Jan 2026 16:59:13 -0400

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education, coauthors Suzanne Estaphan, David Kramer, and Harry Witchel discuss their recently published article, “Navigating the frontier of AI-assisted student assignments: challenges, skills, and solutions.”

This paper presents a framework to effectively design take-home assessments in the generative artificial intelligence (AI) era with four key recommendations to navigate the challenges and opportunities posed by generative AI. From codeveloping AI literacy to fostering human-AI collaboration, the strategies empower educators to promote authentic learning, critical thinking, and ethical AI use. Adaptable to various contexts, these insights help prepare students for an AI-driven future while maintaining academic rigor and integrity.

Navigating the frontier of AI-assisted student assignments: challenges, skills, and solutions

Suzanne Estaphan, David Kramer, and Harry J. Witchel

Advances in Physiology Education 2025 49:3, 633-639

The chick embryo model as an educational tool to explore the effect of alcohol on cardiovascular development

Fri, 23 Jan 2026 12:31:16 -0400

In this episode of the APS Publications Podcast, featuring an article from Advances in Physiology Education, authors Declan McLaughlin, Aisling Keane, and Joe Quinn discuss their recently published article, “The chick embryo model as an educational tool to explore the effect of alcohol on cardiovascular development.” This study explores the use of the chick embryo model as a teaching aid to illustrate connections between anatomy and physiology during development. Providing direct observation opportunities, the model allows students to witness organ formation and the impact of teratogens, focusing on cardiovascular abnormalities associated with fetal alcohol syndrome. The paper outlines practical methodologies to assess developmental outcomes. Its adaptability, affordability, and ability to spark discussions make the model a valuable resource for diverse educational environments.

The chick embryo model as an educational tool to explore the effect of alcohol on cardiovascular development

Declan McLaughlin, Aisling Keane, Joe Quinn, and Nuala Tipping

Advances in Physiology Education 2025 49:2, 438-460

Associations between heart size and anthropometric and cardiovascular indicators: an undergraduate physiology teaching laboratory

Fri, 23 Jan 2026 10:31:22 -0400

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education, coauthors Madyson Hintz and Aisya Ahmad Zamri discuss their recent article, “Associations between heart size and anthropometric and cardiovascular indicators: an undergraduate physiology teaching laboratory.” They share how a hands-on undergraduate lab lets students observe heart measurements with ultrasound, collect body and cardiovascular data, and explore how factors like age, sex, body size, and hand palm diameter relate to heart health.

Associations between heart size and anthropometric and cardiovascular indicators: an undergraduate physiology teaching laboratory

Madyson O. Hintz, Aisya S. Ahmad Zamri, Elizabeth W. Erickson, Frosina Barlev, Sean Coffey, and Regis R. Lamberts

Advances in Physiology Education 2025 49:2, 508-516

Jigsaw technique: will it help Gen Z nursing students?

Fri, 16 Jan 2026 13:12:28 -0400

In this podcast, Dr. Rashmi Chandel discusses the recently published article, "Jigsaw technique: Will it help Gen Z nursing students?" This study examines the effectiveness of the jigsaw technique (JST) as a student-centered learning strategy for engaging Generation Z undergraduate nursing students. Recognizing Gen Z learners’ distinct cognitive styles and preferences, the research compares JST with conventional lectures across four physiology modules using a crossover design. Results showed significantly higher pretest, posttest, and retention scores with JST in most modules, along with strong positive student feedback regarding engagement, understanding, communication, and peer interaction. Overall, the findings suggest that integrating JST into nursing education can enhance learning outcomes while fostering essential interpersonal and professional skills in future nurses.

Jigsaw technique: will it help Gen Z nursing students?

Rashmi Chandel, Anumeha Bhagat, Anita S. Malhotra, Ravi Rohilla, Gurjit Kaur, and Kiran Prakash

Advances in Physiology Education 2025 49:2, 304-313

Active learning to improve numeracy skills and confidence using quizzes in first-year biomedical science undergraduates

Fri, 16 Jan 2026 11:22:12 -0400

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education, Stephen Fitzjohn and Frances MacMillan discuss their recently published article, “Active learning to improve numeracy skills and confidence using quizzes in first-year biomedical science undergraduates.” They share how thoughtfully designed, gamified quizzes in Blackboard helped students practice numeracy skills, build confidence, and achieve significant improvement. The conversation highlights a practical and adaptable teaching approach that can be easily applied to subjects beyond numeracy, offering valuable insights for educators looking to enhance student learning and confidence.

Active learning to improve numeracy skills and confidence using quizzes in first-year biomedical science undergraduates

Stephen M. Fitzjohn, Alice M. Semenenko, and Frances M. MacMillan

Advances in Physiology Education 2025 49:3, 680-685

From anonymity to engagement: the benefits of early-semester student-instructor meetings

Fri, 09 Jan 2026 17:20:33 -0400

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education, James Davis discusses their recently published article, “From anonymity to engagement: the benefits of early-semester student-instructor meetings.”

This study shows that brief, early-semester student-instructor meetings foster stronger connections, increase student participation, and improve self-reported academic performance in large lecture courses. The following article demonstrates how a simple, scalable strategy can transform student-instructor relationships and enhance learning outcomes.

From anonymity to engagement: the benefits of early-semester student-instructor meetings

James T. Davis, Abigail P. Sondreal, Frederick Bauer, and Joseph T. Cornelius

Advances in Physiology Education 2025 49:3, 605-610

Interorgan Insights: Pulmonary Vascular Endothelial Cell Dysfunction Associated With the Nonpulsatile Pulmonary Blood Flow in an Ovine Glenn Model

Thu, 08 Jan 2026 09:23:14 -0400

In this podcast, co-first author Jonathan Hyde discusses the recently published article, ‘Pulmonary Vascular Endothelial Dysfunction is Induced by Nonpulsatile Pulmonary Blood Flow in an Ovine Classic Glenn Model’. The study used an in vivo large animal model combined with ex vivo and in vitro studies to investigate pulmonary vascular endothelial cell dysfunction associated with the Glenn procedure. The results suggest that low, non-pulsatile flow associated with Glenn physiology plays a pivotal role in development of endothelial cell dysfunction.

Pulmonary Vascular Endothelial Dysfunction Is Induced by Nonpulsatile Pulmonary Blood Flow in an Ovine Classic Glenn Model

Jonathan Hyde, Michael A. Smith, Naveen Swami, John H. Hwang, Yenchun Chao, Jason Boehme, Gary W. Raff, Casper Noah Nilsson, Wenhui Gong, Gail H. Deutsch, Eric G. Johnson, Ting Wang, Stephen M. Black, Sanjeev A. Datar, Emin Maltepe, Jeffrey R. Fineman

Comprehensive Physiology 2025 15:6, e70071

https://doi.org/10.1002/cph4.70071

Transcriptome-driven Health-status Transversal-predictors

Wed, 07 Jan 2026 11:00:08 -0400

In this episode of the APS Publications Podcast, Dr. Ralph Rühl discusses his team’s new article in Physiological Genomics, “Transcriptome-driven Health-status Transversal-predictor Analysis for health, food, microbiome and disease markers for understanding of lifestyle diseases.” The article outlines the development of a novel artificial intelligence approach based on machine-learning to predict general health and food-intake parameters. This novel technique, which is based on PBMC transcriptomics from human blood, can predict a wide range of health-related markers.

Todt T, van Bussel I, Afman L, Brennan L, Ivanova DG, Kiselova-Kaneva Y, Thomas EL, Rühl R. Transcriptome-driven Health-status Transversal-predictor Analysis for health, food, microbiome and disease markers for understanding of lifestyle diseases. Physiol Genomics. 2025 Nov 19. doi: 10.1152/physiolgenomics.00026.2025. PMID: 41259124.

The use of AI large language models by university students for assignment preparation

Thu, 18 Dec 2025 11:14:26 -0400

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education, David Van Reyk discusses their study on "The use of AI large language models by university students for assignment preparation." Over 50% used AI for idea generation and drafting. PRC students showed improvements in their grades with the use of AI, while Australian students’ grades remained unchanged. Students support institutional guidance and access for responsible AI use.

The use of AI large language models by university students for assignment preparation

Hui Chen, David Van Reyk, and Brian G. Oliver

Advances in Physiology Education 2025 49:2, 517-525

Educators’ experience and guide to scaffolding generative AI applications throughout a physiology and pharmacology undergraduate laboratory course

Wed, 17 Dec 2025 17:51:20 -0400

In this episode of the APS Publications Podcast, featuring Advances in Physiology Education, coauthors Christine Bell and Oana Birceanu discuss their recently published article, “Educators’ experience and guide to scaffolding generative AI applications throughout a physiology and pharmacology undergraduate laboratory course.” The paper presents a two-pronged approach to reduce GenAI confusion and build AI literacy, research, and critical thinking skills.

Educators’ experience and guide to scaffolding generative AI applications throughout a physiology and pharmacology undergraduate laboratory course

Christine E. Bell and Oana Birceanu

Advances in Physiology Education 2025 49:3, 721-728

From virtual to reality: evaluating student attitudes through VR dissection preparations: a use case

Wed, 17 Dec 2025 11:21:20 -0400

In the latest APS Publications Podcast, featuring Advances in Physiology Education, John Zubek discusses, “From virtual to reality: evaluating student attitudes through VR dissection preparations: a use case.”

VR vs. live dissections: how do students learn best? We explored their experiences to see how tech can complement STEM & healthcare training.

From virtual to reality: evaluating student attitudes through VR dissection preparations: a use case

Sarah Shine, Julia Warznie, Guoli Zhou, and John Zubek

Advances in Physiology Education 2025 49:3, 611-620

From compliance to moduli: clarifying basic mechanical properties of biological tissues

Tue, 16 Dec 2025 16:18:49 -0400

In this episode of the APS Publications Podcast, featuring Advances in Physiology Education, coauthors Serena Kuang and Nora Laban discuss their recently published Illuminations paper “From compliance to moduli: clarifying basic mechanical properties of biological tissues.”

This article advances physiology education by clarifying the basic mechanical property-related terms in physiology, introducing two fundamental terms in material science that are often missing in physiology education, and revealing the interrelationships among these terms. It serves as a handy tool kit for physiology educators, researchers, as well as clinicians to select and apply these terms appropriately based on their needs.

From compliance to moduli: clarifying basic mechanical properties of biological tissues

Nora Laban, Radwa Dawood, and Serena Y. Kuang

Advances in Physiology Education 2025 49:3, 651-658

Implementing core concept teaching in an integrated, clinical presentation model medical school curriculum

Tue, 09 Dec 2025 09:53:57 -0400

In this podcast, coauthors Mary Pelkowski and Gabi Waite discuss their recently published Illuminations article, “Implementing core concept teaching in an integrated, clinical presentation model medical school curriculum”. They outline a practical approach to incorporating physiology core-concept teaching into an integrated, team-taught medical curriculum—combining a clinical presentation model with flipped classroom learning.

Implementing core concept teaching in an integrated, clinical presentation model medical school curriculum

Mary M. Pelkowski, Xiaojun Qi-Lytle, and Gabi N. Waite

Advances in Physiology Education 2025 49:3, 659-666

Interorgan Insights: Role of Diet and Exercise Interventions for MAFLD Outcomes

Mon, 01 Dec 2025 16:07:23 -0400

In this podcast, coauthors Maria Magdalena Quetglas-Llabrés and Manuel Jiménez-García discuss their recently published article, ‘Effects of Combining Exercise and Dietary Shifts on Motor Coordination and Oxidative Markers in a High-Fat Diet Model in Rats.' The article investigated the effect of exercise, alone or with dietary modifications, on high fat diet–induced outcomes in rats of both sexes. Authors overview the methodological approach and discuss key takeaways and next steps.

Effects of Combining Exercise and Dietary Shifts on Motor Coordination and Oxidative Markers in a High-Fat Diet Model in Rats

Manuel Jiménez-García, Maria Magdalena Quetglas-Llabrés, Maria Del Mar Ribas-Taberner, Antoni Sureda-Gomila, David Moranta-Mesquida, Silvia Tejada-Gavela

Comprehensive Physiology 2025;15(6):e70074

https://doi.org/10.1002/cph4.70074

The practical skills passport: a co-curricular program to enhance lab skills confidence in undergraduate neuroscience and biology students

Wed, 26 Nov 2025 12:00:39 -0400

In this episode of the APS Publications Podcast, featuring Advances in Physiology Education, coauthors Anna Smith, Fran der Weduwen, and Thomas Powell discuss their recently published Illuminations paper “The practical skills passport: a co-curricular program to enhance lab skills confidence in undergraduate neuroscience and biology students”. The COVID-19 pandemic limited in-person lab opportunities, impacting students’ skills and confidence. This episode explores the development, implementation, and evaluation of a co-curricular lab skills program designed to help students regain confidence during their return to in-person learning. Findings show that participation in the program had a positive impact on student lab confidence.

The practical skills passport: a co-curricular program to enhance lab skills confidence in undergraduate neuroscience and biology students

Anna E. Smith, Fran der Weduwen, Thomas Powell, and Gayle Doherty

Advances in Physiology Education 2025 49:3, 696-703

Misconception about the application of Dalton’s Law in respiratory physiology

Fri, 21 Nov 2025 17:28:01 -0400

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education, Prof. S. Mehran Hosseini discusses the study, “Misconception about the application of Dalton’s Law in respiratory physiology.”

Dalton’s Law may provide a good example for students to highlight the existence of misconceptions and their effect on gaining new knowledge. The awareness of students about this misconception may improve their learning styles.

Misconception about the application of Dalton’s Law in respiratory physiology

S. Mehran Hosseini

Advances in Physiology Education 2025 49:3, 646-650

Connecting Genes to Physiology: The First 25 Years of Physiological Genomics

Tue, 04 Nov 2025 11:01:41 -0400

In this special episode of the APS Publications Podcast, the founding of Physiological Genomics is discussed in a series of interviews with Drs. Allen W. Cowley, Jr., Bina Joe, and Hilary Coller. These interviews were organized and conducted in September 2025 by Oluwatosin Mautin Akinola (PhD candidate in Molecular Medicine at the University of Toledo, Toledo, OH, United States; https://www.researchgate.net/profile/Oluwatosin-Akinola-2). Full videos of these interviews are available as Supplemental Material in the article.

Joe B, Cowley AW, Garrett MR, Kriegel AJ, Prokop JW, Lee EC, Akinola OM, Coller HA. Connecting Genes to Physiology: The First 25 Years of Physiological Genomics. Physiol Genomics. 2025 Oct 29. doi: 10.1152/physiolgenomics.00207.2025. PMID: 41159925.

Enhancing auditory physiology: simulating unilateral conduction defects to improve understanding of Rinne’s and Weber’s tests

Fri, 31 Oct 2025 13:14:40 -0300

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education, Dr. Raju Suresh Kumar discusses a novel, hands-on simulation designed to teach auditory physiology. By experiencing unilateral conductive hearing loss, students gain deeper insight into auditory masking and sound lateralization. This simple, cost-effective method enhances conceptual understanding and clinical skills, offering strong potential for integration into medical education.

Enhancing auditory physiology: simulating unilateral conduction defects to improve understanding of Rinne’s and Weber’s tests

Raju Suresh Kumar, M. Ganesh Kamath, Rekha Prabhu, and Mohamed Eldigire Ahmed

Advances in Physiology Education 2025 49:3, 689-695

Interorgan Insights: Alcohol-Induced Pathophysiological Outcomes

Thu, 30 Oct 2025 11:23:30 -0300

In this podcast, coauthors Liz Simon, Flavia Souza-Smith, Megan Donovan, Eden Gallegos, Kaitlin Couvillon, and Patricia Molina summarize their recently published review article, "Physiological Mechanisms Vulnerable to Alcohol-Induced Alterations: Role in Chronic Comorbidities." The article describes alcohol's multi-systemic physiological effects on the gastrointestinal, cardiovascular, and immune systems, as well as on energy metabolism that contribute to multiorgan injury and disease burden.

Physiological Mechanisms Vulnerable to Alcohol-Induced Alterations: Role in Chronic Comorbidities

Liz Simon, Kaitlin E. Couvillion, Meagan E. Donovan, Eden M. Gallegos, Flavia M. Souza-Smith, Patricia E. Molina

Comprehensive Physiology 2025 15:5, e70057

https://doi.org/10.1002/cph4.70057

Interorgan Insights: Multi-Organ-On-Chip System to Study Interorgan Communication

Tue, 07 Oct 2025 13:03:53 -0300

In this podcast, coauthors Simon D. Pouwels and Brady Rae discuss their recently published research article, "Interorgan Communication Between Lung and Colorectal Epithelial Cells Studied Using a Novel Multi-Organ-On-Chip System." The article describes development of a novel unidirectional millifluidic multi-organ-on-chip device to study the communication between human lung epithelial cells and colorectal cells following a toxic stimulus. Authors additionally discuss the versatility of the device to study communication across other cell types.

Interorgan Communication Between Lung and Colorectal Epithelial Cells Studied Using a Novel Multi-Organ-On-Chip System

Brady Rae, Verena Bood, Hye-Jin Dijk, Gwenda F. Vasse, Barbro N. Melgert, Anika Nagelkerke, Janette K. Burgess, Dirk-Jan Slebos, Irene H. Heijink, Simon D. Pouwels

Comprehensive Physiology 2025 15:5, e70051

https://doi.org/10.1002/cph4.70051

In Vivo Drosophila Model of CS-induced COPD Phenotypes

Mon, 11 Aug 2025 13:48:29 -0300

In this episode of the APS Publications Podcast, featuring an article from AJP–Regulatory, Integrative and Comparative Physiology, author Periklis Marnas discusses inhalation exposure of adult D. melanogaster to cigarette smoke and changes in physiological parameters and the expression of COPD-associated orthologous genes. The study found that transcriptomic responses were more profound in females, indicating sex-specific responses to inhaled toxicants. Furthermore, enrichment analyses of the differentially expressed genes in females pointed to biomolecules associated with response to nicotine and detoxification. D. melanogaster thus provides a powerful model system to test the efficacy of new potential drugs for COPD treatment.

Marnas P, Lüpold S, Giannakou L, Giannopoulos AS, Hatzoglou C, Gourgoulianis KI, Zarogiannis SG, Rouka E. Modeling COPD in Drosophila melanogaster by cigarette smoke inhalation: functional changes and alterations in the expression of COPD-relevant orthologous genes. Am J Physiol Regul Integr Comp Physiol. 2025 Jul 1;329(1):R13-R19. https://doi.org/10.1152/ajpregu.00056.2025

Racial and Sex Differences in Cardiac Autonomic Function

Mon, 11 Aug 2025 13:28:37 -0300

In this episode of the APS Publications Podcast, featuring an article from AJP–Regulatory, Integrative and Comparative Physiology, authors Ziba Taherzadeh and Claire Kissell discuss the influence of race and sex and Cardiac autonomic function. Their study found that non-Hispanic Black adults living in the United States are more likely to develop cardiovascular disease compared with their non-Hispanic White adult counterparts. These results support that reduced cardiac autonomic function does not manifest early in life among young non-Hispanic Black adults, but rather non-Hispanic Black men had greater spontaneous cardiac baroreflex sensitivity and heart rate variability compared with non-Hispanic White men. No differences were found among women.

Taherzadeh Z, Kissell CE, Young BE, Alhalimi TA, Stephens BY, Kaur J, Kao Y, Brothers RM, Fadel PJ. Cardiac autonomic function in young, healthy adults: Influence of race and sex. Am J Physiol Regul Integr Comp Physiol. 2025 May 1;328(5):R611-R618. https://doi.org/10.1152/ajpregu.00288.2024

PVN Neurons in Estradiol Treated Middle-Aged Mice

Mon, 11 Aug 2025 11:32:02 -0300

In this episode of the APS Publications Podcast, featuring an article from AJP–Regulatory, Integrative and Comparative Physiology, authors Andrea Zsombok, Lucie Desmoulins, and Adrien Molinas discuss the role of estradiol treatment in regulating metabolism and glucose homeostasis. In their study with middle-aged, high-fat diet-fed, ovariectomized female mice, the authors found that liver-related neurons in the hypothalamus became more excitable. Estradiol treatment reduced this excitability, suggesting that midlife estradiol therapy may support healthier brain-liver metabolic regulation.

Molinas AJR, Desmoulins LD, Dugas CM, Williams GL, Kamenetsky S, Felintro de Souza V, Maroteaux MJ, Davis RK, Daniel JM, Schrader LA, Zsombok A. Midlife estradiol treatment reduces the firing rate of liver-related PVN neurons in ovariectomized high-fat diet-fed mice. Am J Physiol Regul Integr Comp Physiol. 2025 Aug 1;329(2):R245-R252. https://doi.org/10.1152/ajpregu.00117.2025

Gut Microbes, Risperidone, and a New Therapeutic Path

Wed, 30 Jul 2025 17:03:51 -0300

In this episode of The APS Publications Podcast, coauthors Matthew A. Hadiono, Alexis B. Kazen, Fatima A. Aboulalazm, and John R. Kirby discuss their recent study, "Reutericyclin mitigates risperidone-induced suppression of anaerobic energy expenditure," published in AJP–Regulatory, Integrative and Comparative Physiology.

The authors explore how the gut microbiome, a thermogenic biomass, plays a critical role in regulating energy expenditure. Their study shows that the composition of the microbial community, influenced by both xenobiotics and bacterial metabolites, can impact metabolic function. They found that treatment with reutericyclin counteracts the suppression of anaerobic energy expenditure caused by risperidone. These findings suggest that reutericyclin may offer a new therapeutic approach for managing obesity.

Tune in to learn more about the gut microbiome’s role in energy balance and the potential for microbiota-targeted therapies.

Reutericyclin mitigates risperidone-induced suppression of anaerobic energy expenditure Matthew A. Hadiono, Alexis B. Kazen, Fatima A. Aboulalazm, Colin M. L. Burnett, John J. Reho, Tammy L. Kindel, Justin L. Grobe, and John R. Kirby

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2025 328:6, R741-R757

The Link Between Vitamin D and Sleep

Wed, 30 Jul 2025 16:35:15 -0300

In this episode of The APS Publications Podcast, coauthors John J. Durocher and Ezra Mutai discuss the Editorial Focus titled "Sleep tight with vitamin D’s might" published in AJP–Regulatory, Integrative and Comparative Physiology. The conversation centers on a recent study by Culver et al., which examines the relationship between vitamin D levels and reduced sleep variability.

Tune in to hear how these findings shed light on the potential link between vitamin D status and consistent sleep patterns.

Sleep tight with vitamin D’s might John J. Durocher and Ezra Mutai

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2025 328:5, R557-R558

Exploring CYP450 Pathways in Functional Sympatholysis

Wed, 30 Jul 2025 14:49:53 -0300

In this episode of The APS Publications Podcast, coauthors Alexander A. Buelow and J. Mikhail Kellawan discuss their recent study, "Inhibition of CYP450 pathways reduces functional sympatholysis in healthy young adults," published in AJP–Regulatory, Integrative and Comparative Physiology.

They explore how functional sympatholysis, which has traditionally been considered independent of nitric oxide and prostaglandins, may actually involve endothelial CYP450 pathways. Their findings show that inhibition of CYP450-2C9 reduces sympatholytic responses during dynamic handgrip exercise combined with lower body negative pressure. This suggests that CYP450 plays an important role in regulating blood flow during exercise in healthy individuals.

Tune in for insights into vascular physiology, research methodology, and the broader implications of these findings for cardiovascular research.

Inhibition of CYP450 pathways reduces functional sympatholysis in healthy young adults Alexander A. Buelow, Jacob E. Matney, Sarah M. Skillett, John D. Ashley, Jiwon Song, Chris Mixon, Amir Akbari Fakhrabadi, Matthew Stanford, Debra A. Bemben, Daniel J. Larson, and J. Mikhail Kellawan

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2025 328:6, R642-R650

Interorgan Insights: Leukotrienes in Asthma-IBD Axis

Mon, 28 Jul 2025 18:37:35 -0300

In this podcast, coauthors Emma Elizabeth Sabu Kattuman, Lakshminarayan Reddy Teegala, Somayeh Darzi, Charles K Thodeti, and Sailaja Paruchuri talk about their recently published review, "Leukotrienes: bridging the inflammatory gap in asthma and inflammatory bowel diseases (IBD)." The review highlights how altered leukotriene biosynthesis and signaling contribute to the pathogenesis of both asthma and IBD, and considers the therapeutic implications of targeting leukotriene pathways for patients with concurrent asthma and IBD.

Leukotrienes: Bridging the Inflammatory Gap in Asthma and Inflammatory Bowel Diseases (IBD)
Emma Elizabeth Sabu Kattuman, Lakshminarayan Reddy Teegala, Somayeh Darzi, Charles K Thodeti, Sailaja Paruchuri

Comprehensive Physiology 2025 15:3, e70022

https://doi.org/10.1002/cph4.70022

Leveraging computer-based simulations and immersive software technologies for enhanced student learning in laboratory medicine

Mon, 21 Jul 2025 16:13:21 -0300

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education, join coauthors Maurizio Costabile and Layla Mahdi as they discuss their study, “Leveraging computer-based simulations and immersive software technologies for enhanced student learning in laboratory medicine.” They share how these digital tools were integrated across a 4-year laboratory medicine degree and how they significantly improved student engagement and understanding. Tune in to hear how this innovative approach can be applied beyond laboratory medicine to benefit a wide range of disciplines.

Leveraging computer-based simulations and immersive software technologies for enhanced student learning in laboratory medicine

Maurizio Costabile, Connie Caruso, Chris Della Vedova, Sheree Bailey, and Layla Mahdi

Advances in Physiology Education 2025 49:2, 338-351

Introducing and validating DramaZoom as a teaching tool for diverse student populations

Wed, 16 Jul 2025 17:54:30 -0300

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education, join coauthors Helena Carvalho and Patricia Halpin as they discuss DramaZoom is a teaching tool paired with a pretest to activate memory. It promotes learning for both medical students and undergraduate students with different majors in the study cohort. DramaZoom creates an opportunity for a fun learning experience that promotes knowledge gain in physiology regardless of whether the teaching setting is face to face or completely virtual. Future research will be done to investigate the long-term retention of content.

Introducing and validating DramaZoom as a teaching tool for diverse student populations

Helena Carvalho, Patricia A. Halpin, Elke Scholz-Morris, Rosa de Carvalho, and Daniel Contaifer Jr.

Advances in Physiology Education 2025 49:2, 386-393

Meeting report: an interdisciplinary approach to addressing anxiety in undergraduate active learning biology courses

Mon, 14 Jul 2025 18:01:36 -0300

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education, coauthor Katelyn Cooper highlights the meeting reports titled “Meeting report: an interdisciplinary approach to addressing anxiety in undergraduate active learning biology courses.” She explains that anxiety is a common emotional condition marked by feelings of tension, worry, and physical symptoms like restlessness and fatigue. Among college students, anxiety is the most reported mental health concern and is linked to lower motivation, engagement, and academic performance. Biology students may be particularly affected due to the rigor and competitiveness of their courses, with high anxiety levels contributing to reduced academic success and increased attrition in the field.

Meeting report: an interdisciplinary approach to addressing anxiety in undergraduate active learning biology courses

Katelyn M. Cooper, Sara E. Brownell, Elisabeth E. Schussler, Virginia R. Downing, Logan E. Gin, Kelly K. McDonald, Randolph M. Nesse, Carly A. Busch, Benjamin J. England, LaToya Grigler, Samantha A. Maas, Marco Molinaro, Nicole L. Nieset, Amy L. Pate, Jed Rasmussen, Jessica L. Schleider, Amina Y. Simmons, Shawn L. Spurgeon, Cynthia M. Stonnington, and Michael Trobiano

Advances in Physiology Education 2025 49:2, 405-415

Uncovering Heightened Cardiovascular Reflexes in Chronic Kidney Disease

Fri, 11 Jul 2025 11:09:52 -0300

In this episode of The APS Publications Podcast, corresponding author Han-Kyul Kim provides an overview of the study titled "Exercise pressor reflex function is augmented in rats with chronic kidney disease," recently published in AJP–Regulatory, Integrative and Comparative Physiology. Dr. Kim discusses how the research team uncovered exaggerated blood pressure responses triggered by the exercise pressor reflex (EPR) in a chronic kidney disease (CKD) animal model. The study highlights how both the muscle mechanoreflex, activated through passive stretch and the muscle metaboreflex, stimulated by intra-arterial capsaicin, contribute to this hypertensive effect. Tune in to learn more about how sympathetic overactivation and altered reflex function could play a key role in cardiovascular risk for individuals with CKD.

Exercise pressor reflex function is augmented in rats with chronic kidney disease Han-Kyul Kim, Juan A. Estrada, Ayumi Fukazawa, Amane Hori, Gary A. Iwamoto, Scott A. Smith, Masaki Mizuno, and Wanpen Vongpatanasin

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2025 328:4, R460-R469

Premed pressure: examining whether premed students experience more academic stress compared to non-premeds

Tue, 01 Jul 2025 17:45:52 -0300

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education, coauthors Jynx Pigart, Tasneem Mohammed, and Katelyn Cooper discuss their study, “Premed pressure: examining whether premed students experience more academic stress compared to non-premeds.” Their research investigates the common perception that premedical students experience higher levels of academic stress than their non-premed peers. The findings revealed no statistically significant differences in reported academic stress between the two groups. However, the study did show that students with lower GPAs were significantly more likely to leave the premed track than those with higher GPAs.

Premed pressure: examining whether premed students experience more academic stress compared to non-premeds

Jynx Pigart, Tasneem F. Mohammed, Theresa Acuña, Shurelia Baltazar, Connor Bean, Michayla Hart, Katelyn Huizenga, Amaris James, Hayleigh Shaw, Kimberly Zsuffa, Carly A. Busch, and Katelyn M. Cooper

Advances in Physiology Education 2025 49:2, 280-290

How Oral Contraceptive Pill Phase Alters Microvascular Response to Local Heating

Fri, 06 Jun 2025 14:36:09 -0300

In this episode of The APS Publications Podcast, we hear from coauthor Casey G. Turner about the study, "Oral contraceptive pill phase alters mechanisms contributing to cutaneous microvascular function in response to local heating." Published in AJP–Regulatory, Integrative and Comparative Physiology, this study investigates the effect of OCP phase on in vivo microvascular endothelium-dependent vasodilation and explores underlying mechanisms. Present findings suggest OCP phase does not affect overall microvascular endothelium-dependent dilation but does affect the underlying mechanisms. In women using OCP, there is a robust reliance on EDHF pathways and the COX pathway moderates basal microvascular blood flow and demonstrates a phase-dependent restraint of the NO pathway.

Oral contraceptive pill phase alters mechanisms contributing to cutaneous microvascular function in response to local heating Casey G. Turner, Anna E. Stanhewicz, Karen E. Nielsen, Jeffrey S. Otis, Rafaela G. Feresin, and Brett J. Wong

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2025 328:3, R374-R385

Preparation strategies for physiology competition: lessons learned from participants of Indonesian Medical Physiology Olympiad

Mon, 02 Jun 2025 15:58:11 -0300

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education. The authors present their study on the Indonesian Medical Physiology Olympiad (IMPhO). This article outlines key strategies for building a successful team in a physiology competition, including effective use of resources, mentorship, teamwork, and faculty guidance. These approaches not only enhance performance in competitive settings but can also be adapted to strengthen study techniques for medical students.

Preparation strategies for physiology competition: lessons learned from participants of Indonesian Medical Physiology Olympiad Mohammad Nizar Maulana, Agde Muzaky Kurniawan, Raden Argarini, Rimbun Rimbun, and Eka Arum Cahyaning Putri

Advances in Physiology Education 2025 49:2, 352-355

Evolving resource use for self-directed learning in physiology among first-year medical students in a classroom setting

Tue, 20 May 2025 15:38:18 -0300

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education, we hear from Dr. Himel Mondal about his recently published paper entitled “Evolving resource use for self-directed learning in physiology among first-year medical students in a classroom setting.” This study reports a shift in educational resource use for self-directed learning (SDL) among medical students after introduction of large language model (LLM) chatbots. Students use multiple sources, with digital tools like search engines and LLM chatbots nearly matching each other as the most preferred resources. Despite the accessibility and efficiency of digital tools, traditional resources like textbooks remain relevant, though less frequently chosen.

Evolving resource use for self-directed learning in physiology among first-year medical students in a classroom setting

Himel Mondal

Advances in Physiology Education 2025 49:2, 394-397

Differentially Expressed Adipose Genes with Obesity

Wed, 14 May 2025 15:59:28 -0300

In this episode of the APS Publications Podcast, featuring Physiological Genomics, join coauthors Ibra Fancher and Malak Alradi as they discuss, “A long-term high-fat diet induces differential gene expression changes in spatially distinct adipose tissue of male mice.” This study explores how a long-term high fat diet affects gene expression in visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) in male mice.

A long-term high fat diet induces differential gene expression changes in spatially distinct adipose tissue of male mice.
Malak Alradi, Hassan Askari, Mark Shaw, Jaysheel D. Bhavsar, Brewster F. Kingham, Shawn W. Polson, and Ibra S. Fancher
Physiological Genomics 2024 Dec 1;56(12):819-832. https://doi.org/10.1152/physiolgenomics.00080.2024

Students Utilize Various Locations for Assignment Deadlines

Fri, 25 Apr 2025 22:00:48 -0300

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education coauthor Patricia Halpin highlights the article titled "Students bypass the syllabus to utilize alternate LMS locations for assignment deadlines." Dr. Halpin highlights how the growing use of learning management systems (LMSs) has changed how students access course information—often leading them to overlook the syllabus entirely. This shift can result in confusion and missed deadlines due to reliance on inconsistent LMS postings. Tune in as she explores why it’s more important than ever for faculty to reintroduce the syllabus on day one and clearly communicate where students should go for the most accurate course information.

Students bypass the syllabus to utilize alternate LMS locations for assignment deadlines Savannah Lopez, Allison Pham, Jeremy L. Hsu, and Patricia A. Halpin

Advances in Physiology Education 2024 48:3, 588-592

Interorgan Insights: Digital Twinning of Interorgan Communications

Tue, 22 Apr 2025 12:30:39 -0300

In this episode of The APS Publications podcast featuring Comprehensive Physiology, we hear from Dr. Lance Fortnow (Illinois Institute of Technology) about his recent Review exploring how artificial intelligence (AI) can play a role in digital twinning of interorgan communication. The human body is an extremely complex system with constant interorgan communication, and AI has been proven effective at modeling complex systems and understanding communication. A digital twin is a complete simulation of a physical process, providing a unique opportunity to simulate real-world physiology and pathophysiological conditions such as aging and various disease states. What role might digital twinning play in researching the effectiveness of therapeutic interventions? Can digital twinning provide a platform for both early career and senior researchers to take a holistic interorgan approach to treating disease? Listen now to find out.

Lance Fortnow Digital Twinning of Interorgan Communications Comprehensive Physiology, published February 9, 2025. DOI: doi.org/10.1002/cph4.70002

Exploring Estradiol, Pulse Wave Velocity, and PTSD in Trauma-Exposed Women

Fri, 04 Apr 2025 14:59:23 -0300

In this episode of the APS Publications Podcast, we’re joined by coauthors Chasity Corbin, Chowdhury Ibtida Tahmin, and Ida T. Fonkoue to discuss their research titled "Estradiol levels are differentially associated with pulse wave velocity in trauma-exposed premenopausal women with and without PTSD." The study investigates how serum estradiol (E2) levels influence pulse wave velocity (PWV) in premenopausal women exposed to trauma, with a particular focus on the impact of posttraumatic stress disorder (PTSD). The researchers discovered that E2 levels predicted PWV only in women without PTSD, even after accounting for factors like menstrual cycle phase, age, body mass index, diastolic blood pressure, and PTSD symptom severity. Additionally, the study found that E2 levels were significantly lower in women with PTSD. Tune in as our guests dive into the details of this important study.

Estradiol levels are differentially associated with pulse wave velocity in trauma-exposed premenopausal women with and without PTSD Chasity Corbin, Chowdhury Ibtida Tahmin, Chowdhury Tasnova Tahsin, Zynab Ahmed, Redeat Wattero, Azhaar Mohamed, Susan B. Racette, Daniel Duprez, and Ida T. Fonkoue

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2025 328:3, R235-R241

Enhancing Inclusion in High-Enrollment Science Courses: The Impact of Sharing Demographic Data

Fri, 28 Mar 2025 13:56:25 -0300

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education coauthors Baylee A. Edwards and Sara E. Brownell discuss their educational research titled "Students respond positively to an instructor collecting and sharing aggregated class demographic data from a survey in a high-enrollment physiology course." This study delves into undergraduate students' perceptions of a high-enrollment physiology course instructor gathering and sharing aggregated demographic data to foster inclusivity. Most students responded positively to this approach, with particular benefits noted by women, nonbinary students, and liberal-leaning students. Edwards and Brownell's findings suggest that collecting and sharing student demographic data in an aggregate form could be an effective strategy to strengthen student-instructor relationships and promote inclusion in large science courses. Tune in to hear more about this impactful research and its potential to transform high-enrollment classrooms.

Students respond positively to an instructor collecting and sharing aggregated class demographic data from a survey in a high-enrollment physiology course Baylee A. Edwards, Jude Kolodisner, Jacob P. Youngblood, Katelyn M. Cooper, and Sara E. Brownell

Advances in Physiology Education 2024 48:4, 836-856

Exploring Epinephrine's Role in EPO Gene Activation During Hypoxia

Fri, 14 Mar 2025 10:51:10 -0300

In this episode of The APS Publications Podcast, featuring AJP-Regulatory, Integrative and Comparative Physiology, coauthors Xiaoyu Su and Nanduri R. Prabhakar dive into their recently published research titled "Adrenal Epinephrine Facilitates Erythropoietin Gene Activation by Hypoxia Through β2 Adrenergic Receptor Interaction with Hif-2α." The study explores the role of sympathetic nervous system (SNS) activation in erythropoietin (EPO) gene expression during hypobaric hypoxia, shedding light on how adrenal epinephrine, via β2 adrenergic receptors, interacts with the transcription factor HIF-2α to enhance EPO gene activation. Tune in as they highlight the breakthrough findings that deepen our understanding of the physiological mechanisms underlying hypoxia-induced gene regulation.

Adrenal epinephrine facilitates erythropoietin gene activation by hypoxia through β2 adrenergic receptor interaction with Hif-2α Xiaoyu Su, Matthew Hildreth, Srikar Rapaka, Ying-Jie Peng, Jayasri Nanduri, and Nanduri R. Prabhakar

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2025 328:1, R75-R80

Advancing Inclusive Education in Reproductive Physiology

Tue, 11 Mar 2025 11:45:47 -0300

In this episode of The APS Publications Podcast, featuring Advances in Physiology Education coauthors Nicholas Fimognari, Leaf R. Kardol, and Caitlin S. Wyrwoll discuss their published paper, “Inclusion of Genital, Sexual, and Gender Diversity in Human Reproductive Teaching: Impact on Student Experience and Recommendations for Tertiary Educators.”

The coauthors outline key teaching innovations aimed at improving inclusivity in reproductive biology and physiology education. By enhancing representation of genital, sexual, and gender diversity in the curriculum, these advancements play a crucial role in shaping the perspectives of future medical professionals and researchers. Tune in as the coauthors explore how inclusive teaching practices can positively impact student experiences and ultimately contribute to more equitable healthcare and research.

Inclusion of genital, sexual, and gender diversity in human reproductive teaching: impact on student experience and recommendations for tertiary educators Nicholas Fimognari, Leaf R. Kardol, Terese O’Shannassy, Katherine A. Sanders, Jeremy T. Smith, and Caitlin S. Wyrwoll

Advances in Physiology Education 2024 48:4, 698-703

Interorgan Insights: Glucagon-Like Peptide-1 Links Ingestion, Homeostasis, and the Heart

Tue, 04 Mar 2025 09:58:27 -0400

Glucagon-like peptide-1 (GLP-1), a hormone released from enteroendocrine cells in the distal small and large intestines in response to nutrients and other stimuli, not only controls eating and insulin release, but is also involved in drinking control as well as renal and cardiovascular functions. This review from Comprehensive Physiology details GLP-1's roles in these interconnected systems, highlighting recent findings and unresolved issues, and integrating them to discuss the physiological and pathological relevance of endogenous GLP-1 in coordinating these functions.

Glucagon-Like Peptide-1 Links Ingestion, Homeostasis, and the Heart.

Jean-Philippe Krieger, Derek Daniels, Shin Lee, Svetlana Mastitskaya, Wolfgang Langhans. Comprehensive Physiology 15: e7. https://doi.org/10.1002/cph4.7

Don't Sleep on Vitamin D

Mon, 03 Mar 2025 17:32:07 -0400

In this episode of The APS Publications Podcast, featuring AJP-Regulatory, Integrative and Comparative Physiology, join coauthors Austin Robinson and Meral Culver as they delve into their recently published research titled "Do Not Sleep on Vitamin D: Vitamin D is Associated with Sleep Variability in Apparently Healthy Adults." The study explores the intriguing connection between vitamin D levels and sleep health, revealing that individuals with lower circulating vitamin D concentrations experience greater sleep variability compared to those with higher levels. Tune in to learn about the growing body of evidence suggesting an important link between vitamin D status and sleep quality.

Do not sleep on vitamin D: vitamin D is associated with sleep variability in apparently healthy adults Meral N. Culver, Braxton A. Linder, Delaney E. Lyons, Zach J. Hutchison, Catherine L. Garrett, Jessica N. McNeil, and Austin T. Robinson

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2025 328:3, R262-R273

The upside to depression: Undergraduates benefit from an instructor revealing depression in a large-enrollment physiology course

Thu, 23 Jan 2025 12:43:16 -0400

In this episode of The APS Publications Podcast, join Tasneem F. Mohammed, Nolina Doud, Sara E. Brownell, and Katelyn M. Cooper as they discuss their recently published paper, "The Upside to Depression: Undergraduates Benefit from an Instructor Revealing Depression in a Large-Enrollment Physiology Course." In the study, an instructor of a large physiology course openly disclosed her depression to students on two separate occasions. The research explores how this revelation impacted students' perceptions of the instructor, the classroom environment, and their overall experience.

Through a survey of 289 undergraduates, the study found that most students remembered the disclosure, with a significant majority reporting a positive impact. The findings show that for some groups, such as women, LGBTQ+ students, and those with more severe depressive symptoms, the disclosure helped normalize depression and fostered a more inclusive and approachable learning atmosphere. This conversation delves into the implications of instructors revealing their own struggles with mental health, challenging the stigma around depression, and offering new perspectives on building supportive and inclusive educational spaces.

Tune in for a thought-provoking discussion on the power of vulnerability in teaching and its potential to transform student experiences.

The upside to depression: undergraduates benefit from an instructor revealing depression in a large-enrollment physiology course Tasneem F. Mohammed, Nolina Doud, Sara E. Brownell, and Katelyn M. Cooper

Advances in Physiology Education 2024 48:4, 884-897

"All of us are capable, and all of us can be scientists." The Impact of Scientist Spotlight Assignments with Undergraduates in Physiology Courses

Thu, 23 Jan 2025 11:25:02 -0400

In this episode, authors Dax Ovid, Ashley Rose Acosta-Parra, Arsema Alemayehu, Jacob Francisco Gomez, Dathan Tran, and Brie Tripp dive into their recently published research titled “All of us are capable, and all of us can be scientists.” They explore the profound impact of Scientist Spotlight assignments on undergraduate students in physiology courses at an emerging Hispanic-serving institution. These assignments, which highlight counterstereotypical scientists, have been shown to significantly enhance students’ feelings of inclusion and foster a deeper connection to the material. Through engaging conversations, the authors discuss how these initiatives not only change students' perceptions of scientists but also improve the learning experience in both major and non-major physiology courses. Join them as they share insights on how inclusive curricula and supportive teaching practices can positively influence student success and representation in the field of physiology.

“All of us are capable, and all of us can be scientists.” The impact of Scientist Spotlight assignments with undergraduates in physiology courses Dax Ovid, Ashley Rose Acosta-Parra, Arsema Alemayehu, Jacob Francisco Gomez, Dathan Tran, and Brie Tripp

Advances in Physiology Education 2024 48:4, 770-783

The Diamond Framework for Team-based Active Learning for Physiology Courses

Wed, 20 Nov 2024 15:10:51 -0400

In this episode, coauthors Daniela G. L. Terson de Paleville and Staci W. Saner explore their paper on incorporating Team-Based Learning (TBL) into physiology and biomedical sciences education. While TBL has become a popular method for teaching conceptual and procedural subjects, it remains underutilized in these fields. Daniela and Staci provide a step-by-step guide for integrating TBL into physiology courses and introduce their innovative Diamond Framework for TBL. Inspired by Bloom’s taxonomy, this visual taxonomy places "application" at the core, offering a new way to structure learning. Tune in to discover how TBL can transform physiology education and enhance student engagement and learning outcomes.

The Diamond Framework for team-based active learning for physiology courses Daniela G. L. Terson de Paleville and Staci W. Saner

Advances in Physiology Education 2024 48:4, 857-866

Leveraging digital assets: lessons from a 14-year-old isotope tracer course for professional scientists

Wed, 20 Nov 2024 14:52:39 -0400

In this episode, coauthors Eann Malabanan, Owen P. McGuinness, and Kendra H. Oliver dive into their recently published paper, "Leveraging Digital Assets: Lessons from a 14-Year-Old Isotope Tracer Course for Professional Scientists." They explore how the COVID-19 pandemic reshaped scientific training programs, forcing many to pivot to virtual formats due to social distancing and travel restrictions. With a focus on the Isotope Tracers in Metabolic Research course—a long-running training program for scientists—they discuss how the integration of digital assets not only helped maintain engagement during the pandemic but also enhanced post-pandemic in-person training. By reviewing survey data from both virtual and in-person formats, they reveal the surprising value of digital elements in fostering better understanding and engagement, even in well-established programs. Tune in to learn how digital strategies can support diverse learning needs and improve professional development for scientists across the globe.

Leveraging digital assets: lessons from a 14-year-old isotope tracer course for professional scientists Eann Malabanan, Owen P. McGuinness, and Kendra H. Oliver

Advances in Physiology Education 2024 48:3, 661-669

Students' approaches to developing scientific communication skills

Fri, 01 Nov 2024 11:57:30 -0300

Join coauthors E.S. Louise Faber, Kay Colthorpe, Louise Ainscough, and Judit Kibedi in this APS Publications podcast as they delve into their recent paper, "Students’ Approaches to Developing Scientific Communication Skills." In this episode, they explore the strategies and resources that undergraduate science students employ to enhance their science communication abilities. Discover how different approaches can influence academic performance in written assessments and the critical role of explicit guidance and engagement with teaching staff in fostering these essential skills. Tune in for a deep dive into the intersection of education, communication, and scientific literacy, and learn how these findings can inform future teaching practices.

Students’ approaches to developing scientific communication skills E. S. Louise Faber, Kay Colthorpe, Louise Ainscough, and Judit Kibedi

Advances in Physiology Education 2024 48:3, 639-647

Graduate Prospects Explain Undergraduate Program Standing in University League Sports Science Tables

Fri, 20 Sep 2024 16:23:08 -0300

In this episode of the APS Publications podcast, coauthor Ole J. Kemi dives into the recently published article "Graduate prospects explain undergraduate program standing in university league sports science tables." The discussion highlights how university rankings play a crucial role for applicants and stakeholders in evaluating undergraduate programs.

Kemi explains that these rankings assess various criteria affecting student life and future prospects, but the study reveals that graduate prospects—the professional benefits students gain post-graduation—are the most significant factor influencing ranking outcomes. This insight emphasizes the importance of career outcomes in shaping perceptions of program quality and helps guide prospective students in their decision-making process. Tune in to learn more about the implications of these findings for universities and students alike!

Graduate prospects explain undergraduate program standing in university league sports science tables Ole J. Kemi, Victoria Penpraze, Nairn Scobie, and Niall G. MacFarlane

Advances in Physiology Education 2024 48:2, 330-337

Enhancing the understanding of abstract neurophysiology concepts by first-year students at the University of La Réunion

Thu, 12 Sep 2024 12:39:24 -0300

In this episode of The APS Publications podcast, coauthor Emmanuel Bourdon highlights the illuminations article titled "Enhancing the understanding of abstract neurophysiology concepts by first-year students at the University of La Réunion." First-year physiology students can find the subject challenging, struggling to understand abstract concepts without any context. To address this, the authors introduced a pedagogical intervention for first-year medical and health physiology students that aimed to link abstract concepts and a pathological disorder, together with a discussion of a specific therapeutic intervention. This pedagogical intervention was well received by first-year physiology students who better understood how basic nerve physiology concepts can be applied within the clinical setting.

Enhancing the understanding of abstract neurophysiology concepts by first-year students at the University of La Réunion M. Faadiel Essop and Emmanuel Bourdon

Advances in Physiology Education 2024 48:3, 655-660

MitomiRs in hibernating thirteen-lined ground squirrels

Fri, 06 Sep 2024 11:22:39 -0300

In the latest APS Publications Podcast, coauthors Karyn Robichaud, and Brynne Duffy discuss their fascinating research on the altered mitochondrial microRNA profiles in thirteen-lined ground squirrels during hibernation. This study sheds light on the metabolic changes these squirrels undergo during torpor and IBE, revealing 38 liver mitomiRs that differ based on hibernation state.

Mitochondrial microRNA profiles are altered in thirteen-lined ground squirrels (Ictidomys tridecemlineatus) during hibernation Karyn Robichaud, Brynne Duffy, James F. Staples, and Paul M. Craig

Physiological Genomics 2024 56:8, 555-566

Group work enhances belonging in an online course

Mon, 26 Aug 2024 15:33:10 -0300

In this episode of The APS Publications podcast, coauthors Shea E. Carr, Thad E. Wilson, and Jennifer L. Osterhage highlight their education research titled "Assigned group work is associated with increased student motivation and perceptions of belonging in an asynchronous online physiology laboratory course." This study explores the effect of assigned group work in an asynchronous online physiology laboratory course on student motivation and belonging. Students’ perceptions of belonging and competence-related beliefs were higher, and effort and psychological costs were lower, when assigned to groups compared to students not assigned to groups. Students assigned to groups noted peer interactions as the most inclusive aspect of the course, whereas instructor interactions were noted as inclusive by those not assigned group work.

Assigned group work is associated with increased student motivation and perceptions of belonging in an asynchronous online physiology laboratory course Shea E. Carr, Thad E. Wilson, Stacey A. Slone, Leila W. Karanja, and Jennifer L. Osterhage

Advances in Physiology Education 2024 48:3, 593-602

Channel Catfish Transcriptomic Response to Hypoxia

Wed, 14 Aug 2024 15:18:48 -0300

In this episode of The APS Publications Podcast, Brian D. Ott highlights the recently published paper titled "Hypothalamic transcriptome response to simulated diel earthen pond hypoxia cycles in channel catfish (Ictalurus punctatus)." Channel catfish are an economically important species that experience diel episodic periods of hypoxia that can reduce appetite. This is the first study to investigate their transcriptome from the hypothalamus in a simulated 24-h span in a commercial catfish pond, with 12 h of hypoxia and 12 h of normoxia. The research revealed functional groups of genes relating to hypoxia, angiogenesis, and glycolysis as well as individual target genes possibly involved in appetite regulation.

Hypothalamic transcriptome response to simulated diel earthen pond hypoxia cycles in channel catfish (Ictalurus punctatus) Brian D. Ott, Amanda M. Hulse-Kemp, Mary V. Duke, Matt J. Griffin, Brian C. Peterson, Brian E. Scheffler, Eugene L. Torrans, and Peter J. Allen

Physiological Genomics 2024 56:8, 519-530

Drama-Enhanced Medical Physiology Tutorials

Tue, 30 Jul 2024 16:29:28 -0300

Listen to the latest APS Publications Podcast as Seán Roe, Mary K. McGahon, Sharon Parkinson, Etain Tansey, and Paul Murphy discuss an innovative approach to medical education encouraging drama students to take on the role of simulated patients. A cross-disciplinary learning experience not to be missed! This podcast and paper detail how physiology tutorials for early years medical students are transformed by taking the clinical case off the two-dimensional page and instead having the case scenario acted by drama students. This adds context and authenticity. The benefits are twofold: emphasizing the importance of physiology to the budding clinician and embedding empathy and compassion from the earliest points in a clinician’s career.

A cross-disciplinary approach to learning medical physiology and behavioral skills involving drama students performing as simulated patients

Seán Roe, Mary K. McGahon, Sharon Parkinson, Etain Tansey, and Paul Murphy

Advances in Physiology Education, Published 1 June 2024

Alignment of Learning Objectives in Medical Physiology

Fri, 12 Jul 2024 13:13:42 -0300

In this APS Publications Podcast, Lisa Carney Anderson discusses the findings from the paper "Alignment of learning objectives, assessments, and active learning to promote critical thinking in a first-year medical physiology course." This paper highlights the authors' introduction of formative assessments and study techniques to first-year medical students in a physiology course. Mastery of learning objectives was emphasized as the key to success. The students were asked how they studied physiology through an anonymous online survey and focus group interviews. The students enjoyed physiology but had difficulty with exam expectations. Helping students use learning objectives to guide their study may lead to improved exam scores. It may also help administrators meet their curriculum goals.

Alignment of learning objectives, assessments, and active learning to promote critical thinking in a first-year medical physiology course: lessons learned

Lisa Carney Anderson and Carolina Fernandez-Branson Advances in Physiology Education, Published 1 June 2024

Lung miRNA & cytokine expression in HDM challenged FCG mice

Fri, 28 Jun 2024 11:29:23 -0300

In this APS Publications Podcast, Sarah Commodore delves into a study titled "Lung proinflammatory microRNA and cytokine expression in a mouse model of allergic inflammation: role of sex chromosome complement and gonadal hormones." This research explores how microRNAs (miRNAs), which are crucial in gene regulation and environmental interactions, might contribute to sex differences in allergic responses and lung diseases.

The study employed a targeted omics approach to examine how gonadal hormones and chromosomal components influence lung responses to allergen exposure. The findings suggest that sex hormones play a significant role in regulating miRNA expression and proinflammatory markers during allergic airway inflammation. This indicates a complex interplay between genetic (sex chromosome complement) and hormonal factors in shaping immune responses in the lungs.

Lung proinflammatory microRNA and cytokine expression in a mouse model of allergic inflammation: role of sex chromosome complement and gonadal hormones Sarah Commodore, Carolyn Damilola Ekpruke, Dustin Rousselle, Rachel Alford, Maksat Babayev, Shikha Sharma, Aaron Buechlein, Douglas B. Rusch, and Patricia Silveyra

Physiological Genomics 2024 56:2, 179-193

Cracking the Code: Using Educational Gaming for High-Level Thinking in Physiology Education

Fri, 21 Jun 2024 10:18:46 -0300

Tune in to the latest APS Publications Podcast episode where authors Joel Roberts and Jonathan P. Dyhr dive into the world of using gaming as an educational tool! They discuss how a simple word game engaged students in higher level thinking about physiology, making learning fun and challenging.

Joel Roberts, Lise A. Johnson, and Jonathan P. Dyhr Cracking the code: using educational gaming for high-level thinking in physiology education Advances in Physiology Education, Published 13 March 2024

Teaching the Tutors: Use of an OSTE to Train Medical Students to be Peer Tutors

Fri, 14 Jun 2024 10:55:54 -0300

In this episode of the APS Publications Podcast, Judith Litvin highlights the recently published education research titled "Teaching the tutors: use of an OSTE to train medical students to be peer tutors." This novel application of the Objective Structured Teaching Examination (OSTE) was done to enhance tutors’ skills as valued members of our integrated academic support program. The OSTE provided feedback to the tutors and enabled us to identify a need for enhanced tutor training in active learning strategies. The OSTE can be adapted for use in other health science educational programs to enhance their training programs and to assess tutors' skills in preparation for their role.

Christian Schill, Samantha Panich, Mary F. Barbe, Maryellen E. Gusic, and Judith Litvin Teaching the tutors: use of an OSTE to train medical students to be peer tutors Advances in Physiology Education, Published 24 April 2024

FAOPS 2023 Teaching Workshop and Education Symposium

Fri, 31 May 2024 13:32:43 -0300

In this episode of the APS Publications Podcast, Jae Boum Youm highlights the authors' comprehensive report on the 10th Federation of the Asian and Oceanian Physiological Societies Congress (FAOPS 2023) Teaching Workshop and Education Symposium. This year marked a significant milestone in physiology education, focusing on innovative and inclusive teaching methods post-COVID-19. The meeting united educators and experts to redefine physiology teaching, covering inclusive, student-centered learning, humanities integration, and collaboration between basic science educators and clinical educators. It also emphasized the role of emerging technologies such as artificial intelligence (AI)-based evaluation tools, augmented reality (AR) goggles, and apps like Slido, Kahoot, Vevox, Miro, and Padlet in creating interactive, technology-driven learning environments. These technologies align with the evolving needs of modern medical education by providing real-time camera image analysis for human skeleton modeling, gesture recognition systems for physical rehabilitation, and imitation games, as well as facilitating discussion, visualization, and student engagement through interactive quizzes, polls, and case-based flipped classroom approaches. (Note: AI-generated voice was used to record parts of this episode.)

Jae Boum Youm, Hyun Goo Woo, and Noriyuki Koibuchi A comprehensive report on the FAOPS 2023 teaching workshop and education symposium Advances in Physiology Education, Published 23 April 2024

Pharmamemory: An Interactive Learning Tool

Fri, 24 May 2024 11:00:10 -0300

In this episode of The APS Publications podcast, coauthors Frederick Miller and Ryan Jones introduce PharmaMemory: an innovative, interactive web application designed to facilitate learning autonomic physiology and pharmacology. Recognizing the challenges medical students face in grasping complex topics like autonomic pharmacology within tight timeframes, they developed PharmaMemory (www.pharmamemory.com) as a solution. PharmaMemory (www.pharmamemory.com) is a free web application that interactively depicts the effects of high-yield autonomic drugs on the human body.

Timothy Rosencrans, Ryan Jones, Daniel Griffin, India Loyd, Anna Grady, Mary Moon, and Frederick Miller PharmaMemory: an interactive, animated web application for learning autonomic physiology and pharmacology

Advances in Physiology Education, Published online 30 April 2024 DOI: 10.1152/advan.00214.2022

The EMPOWER Program: A History and Guide for Increasing Diversity using Integrated Research and Education

Thu, 16 May 2024 14:57:33 -0300

In this episode of The APS Publications Podcast, Adrienne Lester King discusses the Empower Program. The Engaging Multidisciplinary Professional Opportunities for Women in Environmental Research (EMPOWER) program is a one-of-a-kind research summer experience for minority female high school students in the state of Georgia. In addition, this program provides high school teachers with hands-on experiences that can be adapted to use in the classrooms. This combination of lab and field research immerses participants in understanding urban environmental exposures and their health effects. The EMPOWER program was established to meet the critical need for increasing diversity in science, technology, engineering, and mathematics.

Adrienne Lester King,Cristi Bell-Huff,Collins Airhihenbuwa,Susan Ogletree, and Christa Wright The EMPOWER program: a history and guide for increasing diversity using integrated research and education

Advances in Physiology Education, Published online 24 April 2024

Teaching Critical Thinking in Nutritional Sciences

Fri, 03 May 2024 10:14:48 -0300

Author Tyler B. Becker highlights the paper titled "Teaching critical thinking in nutritional sciences: a model course and assignments." The authors of this paper show that a scaffolded nutrition and health claim assignment helps to teach critical thinking skills among nutritional sciences students. Further, this course example is to serve as a model for STEM majors on how to incorporate case-based and problem-based learning strategies into an undergraduate course.

Tyler B. Becker,Vanessa N. Cardino,James Lucas, andJenifer I. Fenton Teaching critical thinking in nutritional sciences: a model course and assignments

Advances in Physiology Education, Published online 9 April 2024

Physiology Quiz Competition - the Game of Education or Entertainment?

Mon, 25 Mar 2024 09:31:41 -0300

In this episode of The APS Publications Podcast, Hardikkumar Amrutbhai Mistry touches on the topic of competition as a method of teaching and learning physiology that provides education with entertainment in a medical college. The authors of this paper believe it increases students’ interest in the subject of Physiology and helps them to understand and learn the subject effectively.

Hardikkumar Amrutbhai Mistry, Narendra Pathak, Dhvani Desai, Sharvil Dulera, and Rachana Mandli Physiology quiz competition: the game of education or entertainment?

Advances in Physiology Education, Published online 17 January 2024

Adcy3: a Link between Obesity and Depression

Fri, 22 Mar 2024 15:13:48 -0300

In this episode of The APS Publications Podcast, Mackenzie Fitzpatrick, and Leah C. Solberg Woods discuss the recently published Mini-Review "Adenylate cyclase 3: a potential genetic link between obesity and major depressive disorder." In this podcast and associated paper, the authors discuss the role of both Adcy3 and the cAMP/PKA pathway, including specific genetic mutations, in both obesity and major depressive disorder. Understanding the role that Adcy3 mutations play in obesity and MDD could open the door for precision medicine approaches and treatments for both diseases that target this gene.

Adenylate cyclase 3: a potential genetic link between obesity and major depressive disorder Mackenzie Fitzpatrick and Leah C. Solberg Woods

Physiological Genomics 2024 56:1, 1-8

A Primer: How to Address Peer Reviews of Your Manuscript

Mon, 18 Mar 2024 14:39:41 -0300

In this episode of The APS Publications Podcast, Amie J. Dirks-Naylor talks about the Peer Review process as a foundational element of scientific publishing, serving as a mechanism to ensure research quality and rigor. The journey often involves a crucial step, addressing reviews of your manuscript. Peer reviews, although essential for refining your work, can be challenging to navigate. This podcast and paper are designed to help authors approach this process.

Amie J. Dirks-Naylor A Primer: How to Address Peer Reviews of Your Manuscript

Advances in Physiology Education, Published 23 January 2024

Inquiry Based Learning for Intensive Care Medicine

Tue, 12 Mar 2024 09:46:38 -0300

In this episode of The APS Publications Podcast, Aniket Nadkarni, and Rahul Costa-Pinto discuss new insights into the benefits and challenges of an inquiry-based learning (IBL) program in the context of practicing clinicians. An IBL program was launched as part of a novel binational intensive care medicine education program. Postgraduate intensive care medicine practitioners participated in this education intervention, where facilitated group discussions explored core intensive care medicine concepts. Survey responses indicated overall satisfaction, engagement with the IBL format, and a constructivist approach to learning.

Aniket Nadkarni, Rahul Costa-Pinto, Tamishta Hensman, Emily V. Harman, Fumitaka Yanase, Bruce G. Lister, Christopher P. Nickson, and Josephine S. Thomas Evaluating an inquiry-based learning program

Advances in Physiology Education, Published 8 November 2023

Enhancing Respiratory Physiology Education: Innovative Wet Spirometer Modifications for Hands-On Learning

Fri, 08 Mar 2024 10:06:33 -0400

In this episode of The APS Publications Podcast, Lajja Patel discusses the modification of wet spirometers to investigate the fundamental laws of flow and different types of lung disease. This activity involves cost-effective modifications to the wet spirometer, broadening its applicability. These modifications effectively address student challenges associated with wet spirometer handling and enhance comprehension of fluid dynamics, all without the need for costly simulations, wet experiments, or fragile instruments. By offering a hands-on experience without traditional limitations, our modified spirometer provides an accessible and engaging approach to respiratory physiology education.

Prashant Rajdeep, Lajja Patel, Ketaki Poorey, Preeti Panchal, and Susan Yohannan Enhancing respiratory physiology education: innovative wet spirometer modifications for hands-on learning

Advances in Physiology Education, Published January 29, 2024 DOI: 10.1152/advan.00132.2023

Flipped Classroom for Undergraduate Medical Students in India: Are we ready for it?

Thu, 29 Feb 2024 10:15:12 -0400

In this episode of The APS Publications Podcast, Anita S. Malhotra, and Anumeha Bhagat discuss the possibility of flipped classrooms for Undergraduate Medical Students in India. The authors conducted a study to find if flipped teaching model improves the learning of medical undergraduate students and assess students’ perceptions. There was no difference in marks obtained by students taught with either flipped or traditional methods. The reasons for this could be differences in the level of learner, prior exposure, or learner readiness for active learning. Since students prefer the flipped method of classroom teaching, it is feasible to adopt it in the Indian classroom.

Anita S. Malhotra, and Anumeha Bhagat Flipped classroom for undergraduate medical students in India: are we ready for it?

Advances in Physiology Education, Published September 13, 2023 DOI: 10.1152/advan.00200.2022

Predictive modeling of maternal mRNA stability

Fri, 23 Feb 2024 11:55:33 -0400

In this episode of The APS Publications Podcast, Keith E. Latham, discusses the recently published manuscript titled "Predictive modeling of oocyte maternal mRNA features for five mammalian species reveals potential shared and species-restricted regulators during maturation."

NEW & NOTEWORTHY Conservation across species of mRNA features regulating maternal mRNA stability during mammalian oocyte maturation was analyzed. 3′-Untranslated region length and synonymous codon usage are positively associated with stability, while GC content is negatively associated. Just three RNA binding protein motifs were predicted to regulate mRNA stability across all five species examined, but associated pathways and functions are shared, indicating oocytes of different species arrive at comparable physiological destinations via different routes.

Peter Z. Schall and Keith E. Latham Predictive modeling of oocyte maternal mRNA features for five mammalian species reveals potential shared and species-restricted regulators during maturation Physiological Genomics Published December 19, 2023. DOI: 10.1152/physiolgenomics.00048.2023

Unpacking the 'Physiological Adaptation' Core Concept of Physiology

Tue, 20 Feb 2024 13:12:53 -0400

In this episode of The APS Publications Podcast, Suzanne Estaphan discusses the recently published manuscript titled "Unpacking and validating the “physiological adaptation” core concept of physiology." The aim of this study was to unpack the “physiological adaptation” core concept with the descriptor “organisms adjust and adapt to acute and chronic changes in the internal and external environments across the lifespan.”

Suzanne Estaphan, Glenn D. Wadley, Gabrielle Todd, Michelle Towstoless, Deanne H. Hryciw, Louise Lexis, Alan Hayes, Kathy Tangalakis, and Task Force Unpacking and validating the “physiological adaptation” core concept of physiology Advances in Physiology Education, Published October 09 2023. DOI:10.1152/advan.00083.2023

Resilient Pedagogy: Experiences of Kinesiology Faculty during COVID-19

Mon, 12 Feb 2024 15:17:17 -0400

In this episode of The APS Publications Podcast, Jessica K. Fleming, Jennifer L. Caputo, Katie E. Spillios, Astrid E. Mel, Mary C. Stenson, and Samantha L. Johnson discuss their recently published article titled "Resilient pedagogy: experiences of kinesiology faculty during COVID-19." The COVID-19 pandemic caused temporary and permanent changes to higher education, specifically kinesiology programs. This podcast and corresponding article highlights the resiliency of faculty in kinesiology programs, how they adapted, where they felt supported, and what they hope to bring with them into their future pedagogy practices.

Jessica K. Fleming, Jennifer L. Caputo, Katie E. Spillios, Astrid E. Mel, Mary C. Stenson, and Samantha L. Johnson Resilient pedagogy: experiences of kinesiology faculty during COVID-19

Advances in Physiology Education, Published September 13, 2023 DOI: 10.1152/advan.00050.2022

Cellular Diversity in Congenital Heart Disease

Tue, 06 Feb 2024 16:46:55 -0400

In this episode of The APS Publications Podcast, Dr. Richa Tambi and Dr. Binte Zehra discuss the recently published research in Physiological Genomics titled "Single-cell reconstruction and mutation enrichment analysis identifies dysregulated cardiomyocyte and endothelial cells in congenital heart disease."

NEW & NOTEWORTHY Congential heart disease (CHD) is one of the most prevalent neonatal congenital anomalies. We present a comprehensive analysis combining genomics and CHD single-cell transcriptome. Our study identifies 90 potential candidate CHD risk genes of which 6 are novel. The risk genes have heterogenous expression suggestive of multiple genes contributing to the phenotypic heterogeneity of CHD. Cardiomyocytes and endocardial cells are identified as major CHD-related cell types.

Richa Tambi, Binte Zehra, Sharon Nandkishore, Shermin Sharafat, Faiza Kader, Nasna Nassir, Nesrin Mohamed, Awab Ahmed, Reem Abdel Hameid, Samah Alasrawi, Martina Brueckner, Wolfgang M. Kuebler, Wendy K. Chung, Alawi Alsheikh-Ali, Roberto M. Di Donato, Mohammed Uddin, and Bakhrom K. Berdiev Single-cell reconstruction and mutation enrichment analysis identifies dysregulated cardiomyocyte and endothelial cells in congenital heart disease Physiological Genomics, published November 17, 2023 DOI: 10.1152/physiolgenomics.00070.2023

Integrating Physiology and Clinical Undergraduate Teaching

Tue, 06 Feb 2024 15:06:35 -0400

In this episode of The APS Publications Podcast, Dr. Amir Hakim, Dr. William Ricketts, Dr. Paul Pfeffer, and Dr. Rachel Ashworth discuss their Teaching Innovations article published in Advances in Physiology Education. The development of teaching methods that support integrated learning and build student confidence is a priority. An audience response system was used to engage early year medical students in large classes in preparation for teaching within a hospital setting. Results showed high levels of student engagement and a greater appreciation for the link between theory and practice. This study describes a simple, active, and integrated method of learning that improves student confidence in clinical reasoning. To find out more, click play.

Amir Hakim, William Ricketts, Paul Pfeffer, and Rachel Ashworth Integration of respiratory physiology and clinical reasoning in the early years of a medical curriculum: engaging with students in a large classroom setting Advances in Physiology Education, published March 22, 2023. DOI: 10.1152/advan.00116.2022

Teaching Science with Music via Universal Design for Learning Framework

Fri, 02 Feb 2024 12:38:36 -0400

In this episode of The APS Publications Podcast, Dr. Greg Crowther (Everett Community College) and Dr. Lekelia Jenkins (Arizona State University) discuss how instructors and students often find it fun to incorporate music into science classes. However, the casual usage of music in this context can unintentionally convey that science courses are mostly about memorizing scientific facts. In this article, the authors argue for a more nuanced approach to teaching science with music, rooted in Universal Design for Learning (UDL). Ready to sing along to “Welcome to the Human Body” (original song by Greg Crowther)? Listen now.

Gregory J. Crowther, Edmund Adjapong, and Lekelia D. Jenkins Teaching science with the “universal language” of music: alignment with the Universal Design for Learning framework Advances in Physiology Education, published June 15, 2023. DOI: 10.1152/advan.00006.2023

Using Jenga to Teach Students the Impact of Health Behaviors on Community Well-Being

Thu, 25 Jan 2024 16:09:47 -0400

In this episode of The APS Publications Podcast, Dr. Steven Elmer, Dr. Kyle W. Wehmanen, and Dr. Felix E. Cottet-Puinel (all at Michigan Technological University) discuss their Illuminations article published in the Advances in Physiology Education Call for Papers on The Physiology of Obesity. The authors describe how K-12 students played Jenga to learn about the connections between healthy living habits, disease, and community well-being and resilience. Listen now to get inspired.

Kyle W. Wehmanen, Felix E. Cottet-Puinel, Tyler C. Hampton, Gwyn T. Hamlin, Isaac J. Wedig, and Steven J. Elmer Impact of health behaviors on community well-being and resilience: teaching K-12 students with Jenga! Advances in Physiology Education, published May 11, 2023. DOI: 10.1152/advan.00005.2023

Innovative Techniques for Developing an Inclusive Teaching Environment

Tue, 23 Jan 2024 12:48:00 -0400

In this episode of The APS Publications Podcast, Dr. Lourdes Fortepiani (University of the Incarnate Word) and Dr. Susan Marsh (Washington State University) discuss their recently published Personal View. The educational landscape is becoming increasingly diverse, and there is a pressing need to ensure equity and inclusion in the classroom. In this article, we offer innovative techniques addressed during the 2022 Experimental Biology symposium on inclusive teaching and provide six practical recommendations for educators: 1) being intentional about how and what content is taught, 2) not making assumptions about students, 3) not being afraid to introduce students to difficult subjects, 4) designing a pedagogical approach to include all students, 5) being transparent about personal intentions, and 6) adjusting an approach that isn’t working for both teacher and students. To find out more, listen now.

Lourdes A. Fortepiani, and Susan A. Marsh Innovative techniques for developing an inclusive teaching environment Advances in Physiology Education, published October 23, 2023. DOI: 10.1152/advan.00014.2023

Promoting Outreach Through Physiology Chapter Collaboration

Fri, 19 Jan 2024 12:22:13 -0400

In this episode of The APS Publications Podcast, Dr. Steven J. Elmer (Michigan Technological University), Dr. John J. Durocher (Purdue University Northwest), and Dr. Naveen Sharma (Central Michigan University) discuss their Editorial in Advances in Physiology Education. The authors discuss how workforce shortages, misinformation, and lack of trust in science and public health threaten to slow improvements in global health. Accordingly, the promotion of health-focused science outreach is needed more than ever to help cultivate a diverse health workforce and well-informed citizenry. Physiology provides the backbone for the understanding of health, disease, and medicine. Therefore, the physiology community has a critical role to play by enhancing public awareness of science and growing student interest in health-focused careers. This Editorial makes the case for encouraging local and regional physiology outreach and calls upon physiologists and trainees to participate in at least one outreach activity each year. Ready to get engaged? Listen now.

Steven J. Elmer, Cassandra R. Gohn, John J. Durocher, Naveen Sharma Promoting outreach through physiology chapter collaboration Advances in Physiology Education, published June 15, 2023. DOI: 10.1152/advan.00037.2023

Mapping the Core Concepts of Physiology

Wed, 17 Jan 2024 14:34:54 -0400

In this episode of The APS Publications Podcast, Dr. Brianna L. Julien and Dr. Louise Lexis (both at La Trobe University, Bundoora, Australia) discuss the Curriculum Development and Assessment article published by Tangalakis et al. in the Advances for Physiology Education Call for Papers on Physiology Core Concepts. This article represents the first time an existing set of core concepts for physiology, developed by Michael and McFarland (U.S.-based educators), have been mapped against unit (subject) learning outcomes across physiology curricula in Australian universities to gauge uptake and the need for agreement on a set of core concepts in the Australian higher education context. Interested in learning more? Listen now.

Kathy Tangalakis, Brianna L. Julien, Louise Lexis, Deanne H. Hryciw, Colleen J. Thomas, Maja Husaric, Michelle Towstoless, Philip J. MacKinnon,Yuan Miao, Alan Hayes Mapping the core concepts of physiology across Australian university curricula Advances in Physiology Education, published June 15, 2023. DOI: 10.1152/advan.00139.2022

Modified Version of Countercurrent Multiplication

Fri, 12 Jan 2024 11:51:47 -0400

In this episode of The APS Publications Podcast, Dr. Serena Kuang (Oakland University William Beaumont School of Medicine) discusses the recent Illuminations article on how countercurrent multiplication is widely accepted as the mechanism for the generation of the corticopapillary osmotic gradient in the outer medulla of mammalian kidneys, but the current explanations of it in textbooks and the literature are inefficient and incomplete. This leads to confusion for students. This article shares a modified version of countercurrent multiplication with more understandable explanation as a way of motivating peer discussion, further improvement, and future research. To find out more, listen now.

Serena Y. Kuang A better explanation of countercurrent multiplication in the formation of the corticopapillary osmotic gradient in the outer medulla Advances in Physiology Education, published August 10, 2023. DOI: 10.1152/advan.00227.2022

Role of the physiologist in the COVID-19 pandemic

Wed, 10 Jan 2024 14:07:24 -0400

In this episode of The APS Publications Podcast, Dr. Farheen Fatima (ESIC Medical College, India) discusses the recently published Letter to the Editor by Fatima et al. about the role of physiologists during the height of the COVID-19 pandemic, as well as potential future collaborations between physiologists and other medical, engineering, and technology departments for more fruitful results. One example would be gene sequencing, the association with various pathophysiologies, and the determination of risk factors by observing changes in physiological parameters. These can form the basis of prospective or retrospective analytical studies. Listen now to hear more.

Farheen Fatima, and Indla Yogananda Reddy Role of the physiologist in the COVID-19 pandemic Advances in Physiology Education, published September 13, 2023. DOI: 10.1152/advan.00081.2023

Corporatization of Medical Education

Fri, 05 Jan 2024 16:00:05 -0400

In this episode of The APS Publications Podcast, we bring you Dr. Stephen DiCarlo (Michigan State University) discussing his Personal View co-authored with Dr. Heidi L. Lujan. According to the authors, physiology educators should be preparing future physicians to deliver the care we want to receive as patients. This requires training in communication, collaboration, inquiry, discovery, and innovation while developing the habits of the mind and heart that advance the practice of medicine and the health of the public. However, the authors argue that the current “corporatization” of medical education is failing to accomplish this outcome when medical schools adopt corporate models, cut costs, and seek profit-making opportunities without improving what goes on in the classroom. The authors would like to see physiology educators reconnect to the greater purpose and value of learning. Find out more by listening now.

Heidi L. Lujan, and Stephen E. DiCarlo We used to get money to teach students, now we teach students to get money: medical education has become a market with credentials not knowledge the commodity! Advances in Physiology Education, published June 23, 2023. DOI: 10.1152/advan.00065.2023

Omics and Submaximal Work Capacity and Trainability

Thu, 21 Dec 2023 10:23:36 -0400

In this episode of The APS Publications Podcast, we feature Monalisa Hota of Duke-National University of Singapore Medical School, Singapore highlighting the recently published research “Omics-driven investigation of the biology underlying intrinsic submaximal working capacity and its trainability.”

NEW & NOTEWORTHY Multi-omics and in silico explorations of the genes and underlying biology of submaximal exercise capacity and its response to 20 wk of endurance training were undertaken. Prioritized genes were identified: 13 genes for variation in submaximal exercise capacity in the sedentary state and 5 genes for the response level to endurance training, with no overlap between them. Genes and pathways associated with submaximal exercise capacity in the sedentary state are different from those underlying trainability.

Omics-driven investigation of the biology underlying intrinsic submaximal working capacity and its trainability

Monalisa Hota, Jacob L. Barber, Jonathan J. Ruiz-Ramie, Charles S. Schwartz, Do Thuy Uyen Ha Lam, Prashant Rao, Michael Y. Mi, Daniel H. Katz, Jeremy M. Robbins, Clary B. Clish, Robert E. Gerszten, Mark A. Sarzynski, Sujoy Ghosh, and Claude Bouchard

Physiological Genomics 2023 55:11, 517-543

What is the Uterine Secretory Cycle, and why is it important?

Wed, 20 Dec 2023 14:34:13 -0400

In this podcast Kasey M. Schalich and Vimal Selvaraj (both of Cornell University) discuss the recently published research titled “The uterine secretory cycle: recurring physiology of endometrial outputs that setup the uterine luminal microenvironment.”

NEW & NOTEWORTHY This study unravels the recurring sequence of changes within the uterus that supports vital functions (sperm transit and development of preimplantation embryonic stages) during the reproductive cycle in female Ruminantia. These data present new systems knowledge in uterine reproductive physiology crucial for setting up in vitro biomimicry and artificial environments for assisted reproduction technologies for a range of mammalian species.

Article Citation:

The uterine secretory cycle: recurring physiology of endometrial outputs that setup the uterine luminal microenvironment

Kasey M. Schalich, Prasanthi P. Koganti, Juan M. Castillo, Olivia M. Reiff, Soon Hon Cheong, and Vimal Selvaraj

Physiological Genomics 2024 56:1, 74-97

Remote Compared to Face to Face Pathophysiology Teaching

Wed, 20 Dec 2023 13:31:22 -0400

In this episode of The APS Publications Podcast, we shine a spotlight on Dr. Roberto Zatz (University of São Paulo) summarizing the recent study by Haydar et al. The authors were able to make a rare direct comparison of face-to-face and remote strategies for the teaching of undergraduate medical students in renal pathophysiology. Unexpectedly, students who attended the remote course had significantly higher grades than those who had mostly in-person classes. To find out more, listen now.

Ahmed Haydar, Itamar Souza Santos, Luis Carlos Arcon, Mílton de Arruda Martins, Patricia Zen Tempski, and Roberto Zatz Remote vs. face-to-face activities in the teaching of renal pathophysiology in the context of social isolation during the early phase of the COVID-19 pandemic Advances in Physiology Education, published September 25, 2023. DOI: 10.1152/advan.00257.2022

Reasoning Level and Item Context Affect Student Language

Mon, 18 Dec 2023 17:10:10 -0400

In this new episode of The APS Publications Podcast, we spotlight Dr. Megan Shiroda (CREATE for STEM, Michigan State University) about Education Research by Shiroda et al. published in the Call for Papers on Physiology Core Concepts. This article builds on previous research to quantitatively examine student language in written explanations of mass balance across six contexts using constructed response assessments. These results present an evaluation of student mass balance language and provide researchers and practitioners with tools to assist students in constructing scientific mass balance reasoning explanations. Listen to find out more.

Megan Shiroda, Jennifer H. Doherty, Emily E. Scott, and Kevin C. Haudek Covariational reasoning and item context affect language in undergraduate mass balance written explanations Advances in Physiology Education, published September 25, 2023. DOI: doi.org/10.1152/advan.00156.2022

Physical Activity for Freshmen on Academic Probation

Thu, 14 Dec 2023 19:34:59 -0400

In this episode of The APS Publications Podcast, we feature Dr. Brian Leary, Dr. Miriam Leary, and Dr. Daniel Bonner (all at West Virginia University) discussing their Illuminations article published recently in Advances in Physiology Education. By fostering social integration, improving mood and mental well-being, and increasing university retention rates, this pilot project confirmed the feasibility of using upperclassmen as success coaches for a physical activity intervention for academic probation freshmen. To learn more, listen now.

Miriam Leary, Lindsay DiDio, Daniel Bonner, Randy Bryner, and Brian K. Leary Peer-supported physical activity intervention for academic probation freshmen in a physiology-related major: a feasibility study Advances in Physiology Education, published August 10, 2023. DOI: 10.1152/advan.00021.2023

GI Vagus and Hypertension

Thu, 14 Dec 2023 10:05:33 -0400

In this episode, authors Elliott W. Dirr (University of Toledo), Christopher J. Martyniuk (University of Florida), Kevin J. Otto (University of Florida), and Jasenka Zubcevic (University of Toledo) discuss their recently published paper titled “Subdiaphragmatic vagal nerve stimulation attenuates the development of hypertension and alters nucleus of the solitary tract transcriptional networks in the spontaneously hypertensive rat.”

NEW & NOTEWORTHY

Elliott W. Dirr et al. show that stimulation of the ventral subdiaphragmatic vagal nerve branch may be a promising potential approach to treating hypertension. The data are especially encouraging given that rodents received only 30 min per day of intermittent stimulation therapy and in view of the potential of long-term blood pressure effects that are not stimulus-locked.

Article Citation:

Subdiaphragmatic vagal nerve stimulation attenuates the development of hypertension and alters nucleus of the solitary tract transcriptional networks in the spontaneously hypertensive rat

Elliott W. Dirr, Ladan G. Jiracek, David M. Baekey, Christopher J. Martyniuk, Kevin J. Otto, and Jasenka Zubcevic

Physiological Genomics 2023 55:12, 606-617

Critical Thinking in Anatomy and Physiology

Tue, 12 Dec 2023 18:01:37 -0400

In this episode of The APS Publications Podcast, we feature Dr. Erik P. Silldorff, and Dr. Gerald D. Robinson (both at Towson University) discussing their recently published Personal View of critical thinking skills as essential to the effective performance of many careers, particularly those involving healthcare. To aid the development of these skills in physiology, the formation of logical cognitive frameworks needs to be supported via instruction that emphasizes the context of physiological functions (the “why”), as well as the causality of their sequential actions. Within such frameworks, students become capable of cognitive reasoning required to reach intuitive conclusions after system perturbations. Hear more from the authors by listening now.

Erik P. Silldorff, and Gerald D. Robinson Development of critical thinking skills in human anatomy and physiology Advances in Physiology Education, published October 17, 2023. DOI: 10.1152/advan.00131.2023

First-Gen Freshmen Perceived Academic Preparation

Tue, 05 Dec 2023 17:50:38 -0400

In this episode of The APS Publications Podcast, we highlight Education Research published by Leary et al. In this study, the authors proposed several potential avenues by which to support first-generation freshmen’s academic success in physiology programs, including early identification of at-risk students, setting realistic expectations, educating students early and often about evidence-based strategies, and developing academic recovery strategies as needed. Listen to hear Dr. Brian Leary and Dr. Miriam Leary (both at West Virginia University) discuss how their study. This qualitative investigation of first-generation college freshmens’ perceptions of academic preparedness informs the development of potential avenues by which to support first-generation freshmen in physiology programs.

Miriam Leary, David A. Donley, Skylar Watson, Landyn Hewitt, Randy Bryner, Brian K. Leary Perceptions of academic preparedness of first-gen freshmen in a physiology major inform recommendations for program-level academic development initiatives Advances in Physiology Education, published March 1, 2023. DOI: 10.1152/advan.00152.2022

Placental ion channel expression at high altitude

Mon, 04 Dec 2023 15:13:22 -0400

In this podcast authors Ramón A. Lorca and Colleen G. Julian of the University of Colorado Anschutz Medical Campus, discuss the recently published manuscript titled "Altered placental ion channel gene expression in preeclamptic high-altitude pregnancies." Article Citation: Altered placental ion channel gene expression in preeclamptic high-altitude pregnancies Colleen G. Julian, Julie A. Houck, Sahand Fallahi, Litzi Lazo-Vega, Christopher J. Matarazzo, Breea Diamond, Valquiria Miranda-Garrido, Bernardo J. Krause, Lorna G. Moore, Jonathan A. Shortt, Lilian Toledo-Jaldin, and Ramón A. Lorca

Physiological Genomics 2023 55:9, 357-367

Student Perceptions of Research Methodology Group Activity

Wed, 29 Nov 2023 14:06:02 -0400

In this episode of The APS Publications Podcast, we feature Dr. Ravindran Revand and Dr. Simran Kaur (both at All India Institute of Medical Sciences) discussing their Education Research published recently in Advances in Physiology Education. The study by Revand et al. incorporates an innovative approach to inculcate the basic skills of “research methodology” through three goal-oriented participant-centric group exercises: 1) framing a research question, 2) critiquing a research article, and 3) writing a research protocol. The activities encompass components of self-directed learning through unsupervised group dynamics. They focus on critical thinking, acceptance, communication skills, and teamwork during supervised group dynamics. Listen now to learn more.

Ravindran Revand, Simran Kaur, Kishore Kumar Deepak, and Kanwal Preet Kochhar Planning and implementation of participant-centric group activity on research methodology: perceptions of postgraduate medical students in physiology Advances in Physiology Education, published September 13, 2023. DOI: 10.1152/advan.00089.2023

Case Study on Genomic Imprinting

Mon, 27 Nov 2023 15:25:37 -0400

In our latest episode of The APS Publications Podcast, we feature Dr. Lara K. Goudsouzian (DeSales University) and Dr. Stanley M. Lo (University of California at San Diego) discussing their Illuminations article published in Advances in Physiology Education. The authors noted that students often struggle with the concept of genomic imprinting, in part because it violates Mendelian rules of inheritance. Goudsouzian and Lo hypothesized that the use of a case study would help students better learn the topic of genomic imprinting, an abstract phenomenon in molecular biology and genetics. The authors wrote an interrupted case study that focused on genomic imprinting. The case study consisted of three short popular news articles that relate to genomic imprinting followed by a set of questions. Students learned about genomic imprinting and enjoyed doing it when completing this case study. Tune in to find out more.

Lara K. Goudsouzian, Stanley M. Lo A case study on genomic imprinting facilitates student learning Advances in Physiology Education, published February 7, 2023. DOI: 10.1152/advan.00197.2022

Core Principles in Physiology for BSN and BSES Students

Tue, 21 Nov 2023 12:19:07 -0400

In this episode of The APS Publications Podcast, we highlight the study by Dr. Angela L. Mahaffey (Marcella Niehoff School of Nursing, Loyola University Chicago) published in Advances in Physiology Education. This article outlines prelicensure nursing and exercise sciences student perspective examinations of the 2011 Michael-McFarland (M-M 2011) core principles in physiology through an anonymous online survey. Dr. Mahaffey models an updated approach based on qualitative survey responses from first-year nursing students. As a result, Dr. Mahaffey presents a “Top Ten” List of Core Principles of Human Physiology for Undergraduate Health Professions students. Listen to learn more.

Angela L. Mahaffey Examining the impact of the core principles of physiology with prelicensure BSN and BSES students: a qualitative analysis Advances in Physiology Education, published March 22, 2023. DOI: 10.1152/advan.00076.2022

Biography of Graham Hoyle Exploring Depths of Muscle Diversity

Fri, 10 Nov 2023 10:47:28 -0400

In this episode of The APS Publications Podcast, we feature Dr. Scott Medler (St. Bonaventure University), discussing his article about Dr. Graham Hoyle published recently in Advances in Physiology Education. Hoyle was an important neuroscientist, muscle biologist, and zoologist throughout much of the second half of the twentieth century. He was trained by Bernard Katz at University College London and later worked with C.A.G. Wiersma at Caltech. As a professor at the University of Oregon, Hoyle helped found the Institute of Neuroscience and trained many prominent scientists in the fields of neuromuscular biology and neuroethology. Listen now to learn about this preeminent scientist in early studies of neuromuscular biology.

Scott Medler Graham Hoyle (1923–1985): exploring the depths of muscle diversity Advances in Physiology Education, published October 23, 2023. DOI: 10.1152/advan.00098.2023

Identification of factors driving DNA methylation variation

Wed, 08 Nov 2023 15:38:27 -0400

In this podcast Dr. Giulia Protti and Prof. Matteo Pellegrini of the University of California discuss the recently published manuscript titled “The methylome of buccal epithelial cells is influenced by age, sex, and physiological properties”. The authors have developed a quantitative model to assess how the human methylome is associated with several factors and to identify the genomic loci significantly impacted by each trait. In this research they have reported novel health-related factors driving DNA methylation patterns and new site-specific regulations that further elucidate methylome dynamics. The study contributes to a better understanding of the plasticity of the human methylome and unveils novel physiological traits with a potential role in future medical epigenomic investigations.

Article Citation:

The methylome of buccal epithelial cells is influenced by age, sex, and physiological properties

Giulia Protti, Liudmilla Rubbi, Tarik Gören, Ramazan Sabirli, Serkan Civlan, Özgür Kurt, İbrahim Türkçüer, Aylin Köseler, and Matteo Pellegrini

Physiological Genomics

Formative Assessment in Twitter

Fri, 03 Nov 2023 17:50:02 -0300

In this episode of The APS Publications Podcast, we feature Dr. Himel Mondal (All India Institute of Medical Sciences, Deoghar, India), discussing his recently published article by Mondal et al. in Advances in Physiology Education.

The study presents the participation of medical students in Twitter poll-based formative assessment in a rural medical college in India. Despite low participation rates, students found social media-based formative assessment highly effective in increasing their attention during class. The work by Mondal and co-authors also reveals student preferences for alternative platforms like Telegram and Instagram. These insights contribute significantly to understanding the impact and relevance of social media-based formative assessment in diverse educational contexts. Listen now to learn more.

Himel Mondal, Shaikat Mondal, and Nirupama Ray Student perceptions of Twitter poll-based formative assessment in a rural medical college in India Advances in Physiology Education, published September 28, 2023. DOI: 10.1152/advan.00110.2023

Peer Review and the Future of APS Publications

Fri, 22 Sep 2023 10:12:12 -0300

The American Physiological Society celebrates and discusses the theme of Peer Review Week 2023, which is Peer Review and the Future of Publishing. Peer Review Week is an annual global event which shines a spotlight on the role of peer review in scholarly publishing, and brings together individuals, institutions and organizations committed to sharing the central message that good peer review is critical to scholarly communication. In this episode, you'll hear from APS Publications' Editors, along with Colette Bean, APS Chief Publishing Officer, about how APS Publications are at the forefront of the future of peer review.

To learn more about publishing with APS, visit https://journals.physiology.org/submit

To find APS resources for peer reviewers, visit https://journals.physiology.org/reviewers

To learn more about Peer Review Week 2023, visit https://peerreviewweek.wordpress.com