Somaya Zahran is a transplant nephrology fellow at the Mayo Clinic in Rochester.

[03:06] Sensitization in organ transplantation: Assessment of Risk (STAR) 2025 meeting group report

[08:55] The Banff 2024 Kidney Meeting Report: Rejection as a spectrum of phenotypes and focus on differential diagnostic reasoning

[22:17] Normothermic versus hypothermic machine perfusion in kidney transplantation: A randomized controlled trial

[27:36] Gene-edited pig cardiac xenotransplantation as a bridge to allotransplantation in infants: Progress in a pig-to-baboon model

Description:  Hosts Roz and Dr. Sanchez-Fueyo are joined by Cesar Berto to discuss the key articles of the April issue of the American Journal of Transplantation.

Dr. Cesar Berto is an Assistant Professor at the University of Alabama, Birmingham, in the Division of Infectious Diseases

[03:28] Invasive mold infection in heart transplant recipients: A nationwide multicenter matched case–control study between 2008 and 2022 in France

[08:50] Pharmacokinetics, lineage identity, and trafficking of ex vivo expanded polyclonal regulatory T cells in a prospective randomized clinical trial of kidney transplant recipients with allograft inflammation

[20:55] Transmembrane protein 16F-chloride intracellular channel 1 interaction mediates recipient dendritic cell cross-decoration after transplantation

[31:27] Dual costimulation blockade with the CD154-specific fusion protein dazodalibep and belatacept for prophylaxis of kidney allograft rejection

[43:52] Costimulatory blockade and infectious risk in solid organ transplantation

Justin Barr practices abdominal transplant and advanced hepatobiliary surgery at the Ochsner Clinic

Thomas Schlich is the James McGill Professor and Department Chair at McGill University

Susan E. Lederer is the Ronald Numbers Professor of History of Medicine and Bioethics at the University of Wisconsin–Madison

References:

The Origins of Organ Transplantation

Flesh and Blood: Organ Transplantation and Blood Transfusion in Twentieth-Century America

Justin Barr practices abdominal transplant and advanced hepatobiliary surgery at Ochsner Medical Center

[03:13] Implementation of a physician assistant-led recovery model for heart transplantation: Clinical outcomes and programmatic benefits at a high-volume center

[13:54] A 100-year simulation of the National Kidney Registry’s voucher program

[25:32] Risk of deficient mismatch repair colorectal cancer and precursors after kidney transplantation: A nationwide study

[35:09] Predictive value of torque teno virus viral load for BK polyomavirus DNAemia depends on BK polyomavirus–specific humoral immunity in kidney transplant recipients

[42:50] Suppression of cardiac allograft vasculopathy by a macrophage efferocytosis receptor

Juan Pablo Huidobro is an Assistant Professor in Nephrology at Pontifical Catholic University of Chile

[02:52] Evolving landscape of thrombotic microangiopathy in kidney transplant recipients in the post–C5 inhibitor era

[13:22] Erythropoietin prolongs graft survival in mice by counteracting trained immunity

[22:06] A new principle to attenuate ischemia reperfusion injury in kidney transplantation

[33:14] Sustained allogeneic kidney graft operational tolerance despite discontinued conventional immunosuppression after CD19-CAR-T-cell therapy for relapsed/refractory post-transplantation lymphoproliferative disorder

[40:15] Bloodstream Infection Subtypes and Characteristics Comparing Solid Organ Transplant and Non-Transplant Populations

Description:  Hosts Roz and Dr. Sanchez-Fueyo are joined by Dr. Al-Faraaz Kassam to discuss the key articles of the January issue of the American Journal of Transplantation.

Al-Faraaz Kassam is an Assistant Professor in Transplant Surgery at Johns Hopkins University

[03:45] Evaluation of kidney procurement biopsy and machine perfusion on allograft outcomes: A retrospective cohort study of the OPTN database

[11:23] Improving the  histologic detection of donor-specific antibody-negative antibody-mediated rejection in kidney transplants

[23:01] Exosome-primed T cell immunity is facilitated by complement activation

[32:26] Landscape of subclinical rejection in a large international cohort of pediatric kidney transplant (kTx) recipients

[42:19] Donor Heart Preservation at 10°C After Thoracoabdominal Normothermic Regional Perfusion Lowers Rates of Severe Primary Graft Dysfunction and Improves Recipient Transplant Outcomes

Description:  Hosts Roz and Dr. Sanchez-Fueyo are joined by Hannah Bahakel to discuss the key articles of the December issue of the American Journal of Transplantation.

Hannah Bahakel is a Clinical Immunodeficiency fellow at Cincinnati Children’s Hospital Medical Center

[03:34] Higher vs standard mean arterial pressure target in the immediate postoperative period of liver transplantation to prevent acute kidney injury: A randomized clinical trial (LIVER-PAM)

[13:51] Donor-derived cell-free DNA significantly improves rejection yield in kidney transplant biopsies

[26:27] Tolerogenic lung allograft microenvironment suppresses pathogenic tissue remodeling following respiratory virus infection in mice

[37:11] Therapeutic needs in solid organ transplant recipients: The American Society of Transplantation patient survey

[48:19] Impact of kidney function on 200 days of antiviral prophylaxis for cytomegalovirus disease in cytomegalovirus-seronegative recipients of cytomegalovirus-seropositive donor kidneys: Post hoc analysis of a randomized, phase 3 trial of letermovir vs valganciclovir prophylaxis

Christie Rampersad is clinical associate, in the Division of Nephrology at the University of Toronto in the Ajmera Transplant Centre

[03:45] The early impacts of an attempt to standardize kidney procurement biopsy practices

[13:40] The current state of simultaneous heart-liver transplantation in the United States

[20:11] Engaging patients in organ transplant listing meetings: A survey study

[37:32] Single-cell transcriptional landscape of liver transplant rejection reveals tissue persistence of clonally expanded, treatment-resistant T cells

[45:32] Infectious disease surveillance and management in clinical xenotransplantation: Experience with the first human porcine kidney transplant

Description:  Hosts Roz and Dr. Sanchez-Fueyo are joined by Dr. Christina Haugen to discuss the key articles of the October issue of the American Journal of Transplantation.

Dr. Christina Haugen is an Assistant Professor of Surgery at the University of Cincinnati.

[03:28] Renal resistance trajectories during hypothermic machine perfusion in kidneys donated after circulatory death: Associations with donor characteristics and posttransplant outcomes—An analysis of COMPARE trial data

[10:26] Donor-specific mesenchymal stem cell infusion in human and nonhuman primate kidney transplantation

[19:21] Potential targeting of urokinase-type plasminogen activator receptor–formyl peptide receptor signaling to prevent recurrence in posttransplant primary podocytopathies

[30:20] The relationship between cessation of brain and systemic circulation after withdrawal of life-sustaining measures

[36:03] Pretransplant natural antibody levels identify a subset of deceased donor kidney transplant recipients that benefit from infliximab induction

[03:30] Blunted cardiac reserve as a marker of cirrhotic cardiomyopathy—Cardiac outcomes following liver transplantation and comparison to the existing guidelines

[14:18] Back-table intra-arterial administration of C1 esterase inhibitor to deceased donor kidney allografts improves posttransplant allograft function: Results of a randomized double-blind placebo-controlled clinical trial

[25:55] Donor-derived cell-free DNA is associated with the degree of immunosuppression in lung transplantation

[36:24] A two-threshold algorithm using donor-derived cell-free DNA fraction and quantity to detect acute rejection after heart transplantation

[45:00] Cell therapy with human Interleukin 10–producing ILC2s enhances islet function and inhibits allograft rejection

Dr. Dami Ko is an assistant professor at Northeastern University, specializing in post-transplant care and quality of life.

Dr. Katherine Rizzolo is a nephrologist in Boston, MA.

Dr. Leonela Villegas is a Pediatric Nephrologist at Hartford, CT

References:

Long-term impact of immigration status on outcomes in pediatric kidney transplant recipients. 

Successful pathways to liver transplant for undocumented immigrants. 

Undocumented immigrants: A glaring inequity in transplant.

Dr. Sofia Bin is an assistant professor of medical and surgical sciences at the University of Bologna.

[02:46] Gut microbiome alterations precede graft rejection in kidney transplantation patients

[10:31] Molecular diagnosis of kidney allograft rejection based on the Banff Human Organ Transplant gene panel: a multicenter international study

Editorial: Graft biopsy reimagined: Integrating morphology and molecular maps

[22:20] Does a changing donor pool explain the recent rise in the United States kidney nonuse rate?

[32:45] A scintigraphic look at the dead donor rule in donation after the circulatory determination of death with the use of normothermic regional perfusion: A single-center interventional trial

Editorial: Normothermic regional perfusion in donation after circulatory determination of death—Confirming the absence of brain reperfusion

[37:03] Global variation in living donor liver transplantation practices impacts donor and recipient short-term outcomes: initial insights from the International LDLT Registry

[03:48] Liver transplantation for hepatitis D virus/hepatitis B virus coinfection in Italy: an intention-to-treat analysis of long-term outcomes

[13:42] 10 degree C static storage of porcine donation after circulatory death livers improves biliary viability and mitigates ischemia-reperfusion injury

[22:20] Fewer medullary pyramids in the living kidney donor are associated with graft failure in the recipient

[33:35] Microvascular inflammation in kidney allografts: New directions for patient management

MOMOT (Mouse Models in Transplant) articles:

Can mouse kidney transplant models inform mechanisms of injury and acceptance in clinical kidney transplantation?

Best practices in islet transplantation in mice

Dr. Sanchez-Fueyo is a Professor of Hepatology, and the Academic Director of the Institute of Liver Studies, King's College, London.

[02:51] Recipient toll-like receptor 4 determines the outcome of ischemia-reperfusion injury in steatotic liver transplantation in mice

[10:47] Association between everolimus combination therapy and cancer risk after liver transplantation: A nationwide population-based quasi-cohort study

[21:35] Balancing equity and human leukocyte antigen matching in deceased-donor kidney allocation with eplet mismatch

Editorial: Equitable allocation through human leukocyte antigen eplet matching: A promising strategy with several challenges

[32:51] Impact of the lung allocation system score modification by blood type on US lung transplant candidates

Editorial: From flawed to fairer: Reducing blood type bias in lung transplant allocation

Recommended article: The economic value of a transplant nephrologist: The case for improving compensation models

Alissar El Chediak, MD is a transplant nephrologist at UT Southwestern Medical Center.

Jon Odorico, MD is a transplant surgeon at the University of Wisconsin.

Ron Parsons, MD is a transplant surgeon at the University of Pennsylvania.

References:

Generating strategies for a national comeback in pancreas transplantation: A Delphi survey and US conference report

Dr. Alejandra Mendoza is a transplant infectious diseases physician at the University of Utah. Dr. Cameron Wolfe is a professor of medicine in the division of infectious diseases at Duke University.

References:

Clinician Update on Human Cases of H5N1 and Influenza A Virus Surveillance (COCA Calls)

Dr. Timucin Taner is a professor of surgery at Mayo Clinic, Rochester, MN. Dr. Dami Ko is an assistant professor at the School of Nursing at Northeastern University.

[02:51] Development and validation of the Neuro-Score: a specific scale to detect and monitor cognitive impairment in kidney or liver transplant recipients

Editorial: Cognitive impairment after liver and kidney transplant: An easy way to check

[14:16] Randomized trial investigating the utility of a liver tissue transcriptional biomarker in identifying adult liver transplant recipients not requiring maintenance immunosuppression

[20:46] Donor-specific immune senescence as a candidate biomarker of operational tolerance following liver transplantation in adults: Results of a prospective, multicenter cohort study

Editorial: Acquired immune tolerance 2.0

[29:10] Major histocompatibility complex and peptide specificity underpin CD8+ T cell direct alloresponse

Editorial: Direct and indirect allorecognition—not so different after all?

Dr. Rene Bermea is an instructor at Harvard Medical School, and a transplant pulmonologist and intensivist. Dr. Gonzalo Sapisochin is an associate professor of surgery, abdominal transplant and surgical oncology at the University of Toronto, Canada.

[04:31] Generalizability of kidney transplant data in electronic health records — The Epic Cosmos database vs the Scientific Registry of Transplant Recipients

Editorial: Finding actionable information in the universe of data

[14:17] High-dimensional profiling of immune responses to kidney transplant reveals heterogeneous T helper 1 and B cell effectors associated with rejection

Editorial: Multimodal profiling of transplant rejection: Discerning the forest from the trees

[23:02] The ability of an electronic nose to distinguish between complications in lung transplant recipients

[34:58] The Rochester Protocol for living donor liver transplantation of unresectable colorectal liver metastasis: A 5-year report on selection, approval, and outcomes

Dr. Ross Doyle is a consultant nephrologist at Mater Hospital in Dublin, Ireland.

(Mentioned) A blood-based PT-LIFE (Pediatric Liver Transplantation-LIver Fibrosis Evaluation) biomarker panel for noninvasive evaluation of pediatric liver fibrosis after liver transplantation: A prospective derivation and validation study

Editorial: Are we closer to abandoning protocol graft biopsies after pediatric liver transplantation?

(Mentioned) Deceased donor urinary Dickkopf-3 associates with future allograft function following kidney transplantation

[04:08] Cure models, survival probabilities, and solid organ transplantation for patients with colorectal cancer

Editorial: When is it safe to transplant after cancer–adding data to the decision

[11:05] Navigating challenges in recipient selection for end-chain kidneys

[18:00] Severe ischemia-reperfusion injury induces epigenetic inactivation of LHX1 in kidney progenitor cells after kidney transplantation

[28:31] The differential impact of early graft dysfunction in kidney donation after brain death and after circulatory death: Insights from the Dutch National Transplant Registry

[00:02:38] A competing risks model to estimate the risk of graft failure and patient death after kidney transplantation using continuous donor-recipient age combinations

[00:09:00] Donor-derived bartonellosis in solid organ transplant recipients from unhoused donors in Alberta

[00:16:54] Contemporary prevalence and practice patterns of out-of-sequence kidney allocation

Editorial: Out-of-sequence allocation: a necessary innovation or a new inequity in transplantation?

Editorial: Ethical implications of prioritizing utility at all costs: The rise of out-of-sequence transplants

[00:28:18] Association of nonstandardized model for end-stage liver disease score exceptions with waitlist mortality in adult liver transplant candidates

Dr. Sergio Acuna is a clinical instructor in abdominal transplant surgery at the University of Alabama at Birmingham

[03:21] The dangerous precedent of censoring scientific dissemination

[08:45] Long-term ex situ normothermic machine perfusion allows regeneration of human livers with severe bile duct injury

Editorial: Time will tell: Employing long-term normothermic machine perfusion to gain new insight into bile duct regeneration

[14:00] Probable antibody-mediated rejection in kidney transplantation is a rare and challenging phenotype to define: Findings from a single-center study

[19:54] The relationship of microvascular inflammation with antibody-mediated rejection in kidney transplantation

Editorial: Exploring microvascular inflammation and the spectrum of antibody-mediated rejection

[25:56] Long-term persistence of seroprotection against measles following measles-mumps-rubella vaccination administered before and after pediatric liver transplantation

[31:26] Detection of viral RNA and DNA and immune response following administration of live attenuated measles and varicella vaccines in children with chronic liver disease

Dr. Abraham ‘Abe’ Matar is a Transplant Surgery Fellow at the University of Minnesota

[02:15] Economic Evaluation of Weight Loss and Transplantation Strategies for Kidney Transplant Candidates with Obesity

Editorial: Selecting Weight Loss Strategies for Kidney Transplant Candidacy: Weighty decisions

[11:44] Electrostimulation suppresses allograft rejection via promoting lymphatic regulatory T cell migration mediated by lymphotoxin (LT)-LTb receptor signaling

[18:57] Ischemia Reperfusion Responses in Human Lung Transplants at the Single Cell Resolution

[28:36] The suggestion of mitigating disparity in the liver transplantation field among ABO blood type

Dr. Sharon Weeks Groh is a transplant surgeon at Walter Reed

[02:08] Robotic living donor hepatectomy is associated with superior outcomes for both the donor and the recipient compared to laparoscopic or open - A single center prospective registry study of 3,448 cases

[09:34] Public Attitudes to Xenotransplantation: A National Survey in the United States

[18:09] Non-clinical and clinical characterization of MAU868, a novel human-derived monoclonal neutralizing antibody targeting BK polyomavirus VP1

[25:52] Establishing targets for goal-directed anesthesia in renal transplantation: a cohort analysis of high-saliency surgical time-courses.

Editorial: Intraoperative blood pressure management during kidney transplantation: grafts under pressure.

[36:53] Why partial heart transplantation could be regulated as organ transplantation

[00:02:31] Pre-transplant Use of Immune Checkpoint Inhibitors for Hepatocellular Carcinoma: A Multicenter, Retrospective Cohort Study

Editorial: Integrating immune check inhibitors in liver transplantation for hepatocellular carcinoma: The right time and the right patient

[00:11:46] Association of Procurement Technique with Organ Yield and Cost Following Donation After Circulatory Death

Editorial: Dawn Has Arrived, Illuminating Thrilling Opportunities and Fresh Challenges in a New Era of U.S. Transplantation

[00:24:53] Common Definitions and Variables are Needed for the United States to Join the Conversation on Acute on Chronic Liver Failure

[00:33:15] Enhanced role of multipair donor swaps in response to size incompatibility: The first two 5-way and the first 6-way liver paired exchanges

[00:40:15] Comparing the prognostic performance of iBOX and biopsy-proven acute rejection for long-term kidney graft survival

[00:48:22] Incomplete reporting of clinically significant acute rejection episodes in the National Kidney Transplant Registry

Alissar El Chediak, MD is a transplant nephrologist at UT Southwestern

[02:55] – Liver Machine Perfusion Technology: Expanding the Donor Pool to Improve Access to Liver Transplantation

[08:01] – Editorial: Machine perfusion and liver transplant center behavior: Answers or more questions?

[11:01] - Obesity, Organ Failure, and Transplantation: A Review of the Role of Metabolic and Bariatric Surgery in Transplant Candidates and Recipients.

[18:48] – Virus Specific T Cell Therapy to Treat Refractory Viral infections in Solid Organ Transplant Recipients

[25:08] - Third-party virus-specific T cells for the treatment of double-stranded DNA viral reactivation and posttransplant lymphoproliferative disease after solid organ transplant

[28:48] – Editorial: Virus-specific T-cell efficacy after solid organ transplantation: more questions than answers

[34:05] - Successful BK virus–specific T cell therapy in a kidney transplant recipient with progressive multifocal leukoencephalopathy

[37:50] - The prevalence of postacute sequelae of coronavirus disease 2019 in solid organ transplant recipients: Evaluation of risk in the National COVID Cohort Collaborative

[01:57] Impact of deceased organ donor marijuana use on donor culture positivity and solid organ transplant recipient outcomes https://doi.org/10.1016/j.ajt.2024.02.022

[13:11] China Issued Rules on Human Organ Donation and Transplantation https://doi.org/10.1016/j.ajt.2024.04.002

[21:10] Advancing Mouse Models for Transplantation Research https://doi.org/10.1016/j.ajt.2024.01.006

[30:05] Differential induction of donor-reactive Foxp3+ Treg via blockade of CD154 vs. CD40 https://doi.org/10.1016/j.ajt.2024.03.033

[40:27] Total Robotic Liver Transplant: The Final Frontier of Minimally Invasive Surgery https://doi.org/10.1016/j.ajt.2024.03.030

[03:33] Biliary complications after adult-to-adult living-donor liver transplantation: An international multicenter study of 3633 cases https://doi.org/10.1016/j.ajt.2024.02.023 

[13:07] The impact of time to death in donors after circulatory death on recipient outcome in simultaneous pancreas-kidney transplantation https://doi.org/10.1016/j.ajt.2024.02.008 

[24:30] Should advanced perfusion be the standard of care for donation after circulatory death liver transplant? https://doi.org/10.1016/j.ajt.2024.03.021 

[32:20] Immunosuppression Withdrawal in Living-donor Renal Transplant Recipients Following Induction with Anti-thymocyte Globulin and Rituximab: Results of a Prospective Clinical Trial https://doi.org/10.1016/j.ajt.2024.03.007 

[40:30] Spatial multiomics of arterial regions from cardiac allograft vasculopathy rejected grafts reveal novel insights into the pathogenesis of chronic antibody-mediated rejection https://doi.org/10.1016/j.ajt.2024.01.004 

References

Stewart et al. “Does anyone really know what (the kidney median waiting) time is?”  

Noreen et al. “Augmenting the United States transplant registry with external mortality data: A moving target ripe for further improvement”

Shifman et al. “Association of state Medicaid expansion policies with pediatric liver transplant outcomes”

[3:16] The respiratory syncytial virus vaccines are here: Implications for solid organ transplantation

[19:14] Association between cytomegalovirus viremia and long-term outcomes in lung transplant recipients

[35:40] Genetic versus self-reported African ancestry of the recipient and neighborhood predictors of kidney transplantation outcomes in 2 multiethnic urban cohorts

[EDITORIAL] Untangling genetic and environmental risks in kidney transplant outcomes: The interplay of self-identified race, genetic ancestry, monogenic risk alleles, and socioeconomic factors

[45:15] Low-affinity CD8+ T cells provide interclonal help to high-affinity CD8+ T cells to augment alloimmunity

[53:44] Outcomes in solid organ transplant recipients with a pretransplant diagnosis of melanoma

[2:34] Abdominal computed tomography measurements of body composition and waitlist mortality in kidney transplant candidates

[14:09] A2/A2B to B deceased donor kidney transplantation in the Kidney Allocation System era

[24:01] Xenotransplantation Papers

[25:07] Xenotransplantation experiments in brain-dead human subjects–A critical appraisal

[28:11] The decedent model: A new paradigm for de-risking high stakes clinical trials like xenotransplantation

[32:45] Exploring the single-cell immune landscape of kidney allograft inflammation using imaging mass cytometry

[2:39] Transplanting old organs promotes senescence in young recipients

[11:33] The Banff 2022 Kidney Meeting Report: Reappraisal of microvascular inflammation and the role of biopsy-based transcript diagnostics

[15:45] The Banff 2022 Kidney Meeting Work Plan: Data-driven refinement of the Banff Classification for renal allografts

(Editorial) [18:12] The Banff process—Reloaded: A joint initiative from the Banff Foundation for Allograft Pathology and the American Journal of Transplantation

[20:25] Antiobesity pharmacotherapy to facilitate living kidney donation

[27:04] Ambient air pollution is associated with graft failure/death in pediatric liver transplant recipients

[2:53] Pure laparoscopic donor hepatectomy: Experience of 556 cases at Seoul National University Hospital

[11:26] Smoking exposure-induced bronchus-associated lymphoid tissue in donor lungs does not prevent tolerance induction after transplantation & Aging exacerbates murine lung ischemia-reperfusion injury by excessive inflammation and impaired tissue repair response

[20:28] Augmenting the Unites States transplant registry with external mortality data: A moving target ripe for further improvement

(Editorial) How hard are the hard outcomes reported in national transplant registries?

[32:25] Maintaining the permanence principle of death during normothermic regional perfusion in controlled donation after the circulatory determination of death: Results of a prospective clinical study

Guest speakers include Joel Adler (Dell Medical School, University of Texas in Austin) and John Friedewald (Northwestern Memorial Hospital).

[2:43] Recurrent atypical antiglomerular basement membrane nephritis in the kidney transplant

[14:26] Pretransplantation coronavirus disease 2019 vaccination requirements: A matched case-control study of factors associated with waitlist inactivation

(Editorial) Coronavirus disease 2019 vaccine mandates and the Owl of Minerva

[21:45] Incomplete tissue product tracing during an investigation of a tissue-derived tuberculosis outbreak

[29:48] Risk for graft loss in pediatric and young adult kidney transplant recipients due to recurrent IgA nephropathy

[37:07] De novo membranous nephropathy in a pig-to-baboon kidney xenograft: A new xenograft glomerulopathy

[03:03] Predicting post–liver transplant outcomes in patients with acute-on-chronic liver failure using Expert-Augmented Machine Learning

[10:34] Clinical features, treatment, and outcomes of mpox in solid organ transplant recipients: A multicenter case series and literature review

[14:05] First case of rapidly fatal mpox from secondary (household) transmission in a kidney transplant recipient

[15:28] A joint program of antimicrobial stewardship and hospital-acquired infection control to reduce healthcare-associated infections after kidney transplantation: The Hipomenes study

[22:55] A rational approach to guide cost-effective de novo donor-specific antibody surveillance with tacrolimus immunosuppression

[30:04] (Editorial) Personalizing kidney transplant donor-specific antibody surveillance: The devil is in the details

[33:20] Donor antigen-specific regulatory T cell administration to recipients of live donor kidneys: A ONE Study consortium pilot trial

[03:30] Disseminated vaccine-induced varicella infection in a kidney transplant recipient

[06:50] Safety and Immunogenicity of the Live-Attenuated Varicella Vaccine in Pediatric Solid Organ Transplant Recipients: A Systematic Review and Meta-Analysis

[10:34] (Editorial) Balancing the live virus vaccine scales: protection vs risk

[14:22] Outcomes after flow cytometry crossmatch-positive lung transplants managed with perioperative desensitization

[19:25] Lung transplantation despite preformed donor-specific anti-HLA antibodies: 9-year single-center experience

[23:00] (Editorial) What is a Clinically Significant Donor-Specific Antibody Before Lung Transplantation?

[25:38] Deceased Donor Kidneys from Higher Distressed Communities are Significantly Less Likely to be Utilized for Transplantation

[35:11] (Editorial) Understanding the mechanisms and implications of the association between community distress and organ non-utilization

[37:18] Sex as a Biological Variable: Mechanistic Insights and Clinical Relevance in Solid Organ Transplantation

[2:24] Importance of social vulnerability on long-term outcomes after heart transplantation

[12:51] Microbiota-dependent and -independent effects of obesity on transplant rejection and hyperglycemia

[21:26] Memory T follicular helper cells drive donor-specific antibodies independent of memory B cells and primary germinal center and alloantibody formation

[28:52] Validation of a prediction system for risk of kidney allograft failure in pediatric kidney transplant recipients: An international observational study

[36:44] Qualifying a novel clinical trial endpoint (iBOX) predictive of long-term kidney transplant outcomes

[2:45] Identifying and understanding variation in population-based access to liver transplantation in the United States

[12:44] Intra-graft B cell differentiation during the development of tolerance to kidney allografts is associated with a regulatory B cell signature revealed by single cell transcriptomics

[18:21] Single-cell RNA sequencing reveals peripheral blood mononuclear immune cell landscape associated with operational tolerance in a kidney transplant recipient

[22:20] Impact of allele-specific anti-HLA class I antibodies on organ allocation

[28:12] Autoantibodies against DNA-topoisomerase I promote renal allograft rejection by increasing alloreactive T cell responses

[2:40] In a real-life setting, risk factors, Coronary artery calcium score and coronary stenosis at Computed Tomography Angiography are associated with MACE and all-cause mortality among kidney transplant candidates

[16:00] The minimum weight and age of kidney donors: En bloc kidney transplantation from preterm neonatal donors weighing less than 1.2kg to adult recipients

[24:35] Increased volume of organ offers and decreased efficiency of kidney placement under circle-based kidney allocation

[31:07] Recipient Race Modifies the Association between Obesity and Long-term Graft Outcomes After Kidney Transplantation

Bernards et al. AJT: https://pubmed.ncbi.nlm.nih.gov/35871752/

Kim et al. Meld 3.0: https://pubmed.ncbi.nlm.nih.gov/34481845/

Meld 3.0 calculator: https://medcalculators.stanford.edu/meld

Rodriguez-Peralvarez et al. GEMA: https://pubmed.ncbi.nlm.nih.gov/36528041/

GEMA calculator: http://gema-transplant.com/

[2:33] Xenorecognition and costimulation of porcine endothelium-derived extracellular vesicles in initiating human porcine-specific T cell immune responses

[11:28] The tele-liver frailty index (TeLeFI): development of a novel frailty tool in patients with cirrhosis via telemedicine

[21:18] The 20-year paradigm shift toward organ recovery centers: 2500 donors at Mid-America Transplant and broader adoption across the United States

[33:13] Outcomes of lung and liver transplantation after simultaneous recovery using abdominal normothermic regional perfusion in donors after the circulatory determination of death versus donors after brain death

[42:17] Stakeholders’ perspectives on transplant metrics: the 2022 Scientific Registry of Transplant Recipients’ consensus conference

[1:30] The evolving use of biomarkers in heart transplantation: Consensus of an expert panel

[9:49] Effects of in vivo CXCR4 Blockade and Proteasome Inhibition on Bone Marrow Plasma Cells in HLA Sensitized Kidney Transplant Candidates

[16:50] An ethical analysis of obesity as a contraindication to pediatric liver transplant candidacy

[23:53] Racial and ethnic disparities in psychosocial evaluation and liver transplant waitlisting

[01:59] Genetic evaluation of living kidney donor candidates: A review and recommendations for best practices

[11:36] Mutations In Latent Membrane Protein 1 of Epstein-Barr Virus are Associated with Increased Risk for Post-Transplant Lymphoproliferative Disorder in Children

[23:13] Impacts of removing race from the calculation of the Kidney Donor Profile Index

[31:49] The Association of Donor Hepatitis C Virus Infection with Three-Year Kidney Transplant Outcomes in the Era of Direct-Acting Antiviral Medications

[41:40] Time to discard the term “discard”

[02:01] Successful pathways to liver transplant for undocumented immigrants, Kerznerman et al

[10:30] Effect of vitamin K supplementation on serum calcification propensity and arterial stiffness in vitamin K-deficient kidney transplant recipients: A double-blind, randomized, placebo-controlled clinical trial, Eelderink et al

[18:07] ABO Genotyping finds more A2 to B kidney transplant opportunities than lectin-based subtyping, Joseph et al

[29:15] Oxidative stress and related metabolic alterations are induced in ex situ perfusion of donated hearts regardless of the ventricular load or leukocyte depletion, Hatami et al

[2:57] Milestones on the path to clinical pig organ xenotransplantation, Cooper & Pierson.

[12:45] Infection and clinical xenotransplantation: Guidance from the Infectious Disease Community of Practice of the American Society of Transplantation, Mehta et al.

[20:30] Addressing sex-based disparities in solid organ transplantation in the United States – a conference report, Sawinski et al.

[33:45] A comparison of deprivation indices and application to transplant populations, Park et al.

[1:42] BK DNAemia and native kidney polyomavirus nephropathy following lung transplantation, Dube et al

[12:05] Mortality among solid organ transplant recipients with a pretransplant cancer diagnosis, Hart et al

[24:04] Does Anybody Really Know What (the Kidney Median Waiting) Time Is?, Stewart et al

[32:37] Honoring the gift: the transformative potential of transplant-declined human organs, Albert et al

[37:46] American Society of Transplant Surgeons recommendations on best practices in donation after circulatory death organ procurement, Croome et al

[2:05] Days alive and out of hospital following liver transplant: Comparing a patient-centered outcome between DCD and DBD graft recipients, Frasco et al

[11:03] Acute liver failure and unique challenges of pediatric liver transplantation amid a worldwide cluster of adenovirus-associated hepatitis, Banc-Husu et al

[21:36] Information Design to Support Growth, Quality, and Equity of the U.S. Transplant System, Perakslis and Knechtle

[29:01] Optimum timing of anti-thymocyte globulin in relation to adoptive Treg cell therapy, Muckenhuber et al

We would love to hear your feedback on our podcast, a short survey may be found at http://bit.ly/ajtpod

Dual blockade of the PI3K/Akt/mTOR pathway inhibits posttransplant Epstein‐Barr virus B cell lymphomas and promotes allograft survival, Sang et al: https://onlinelibrary.wiley.com/doi/full/10.1111/ajt.15216

The VA Transplant Program: A rebuttal to criticism and a look to the future, William Gunnar: https://onlinelibrary.wiley.com/doi/full/10.1111/ajt.15295

Prolongation of allograft survival by passenger donor regulatory T cells, Harper et al: https://onlinelibrary.wiley.com/doi/full/10.1111/ajt.15212

Liver transplantation for hepatitis C virus (HCV) non‐viremic recipients with HCV viremic donors, Kwong et al: https://onlinelibrary.wiley.com/doi/full/10.1111/ajt.15162

Functional status at listing predicts waitlist and posttransplant mortality in pediatric liver transplant candidates, Perito et al: https://onlinelibrary.wiley.com/doi/full/10.1111/ajt.15203

The clinical and pathological significance of borderline T cell–mediated rejection, Nankivell et al: https://onlinelibrary.wiley.com/doi/full/10.1111/ajt.15197

Exercise increases skin graft resistance to rejection, Rael et al: https://onlinelibrary.wiley.com/doi/full/10.1111/ajt.15266